Results 261 to 270 of about 378,455 (346)

From Lab to Market: Paper‐Based CRISPR Diagnostics and Commercialization Pathways

open access: yesAdvanced Sensor Research, Volume 4, Issue 10, October 2025.
Paper‐based CRISPR diagnostics represents one of the most widely commercialized CRISPR assay technologies, yet challenges remain for broader point‐of‐care use. Abstract The global health landscape is continually challenged by infectious diseases that can swiftly escalate into pandemics, underscoring the need for rapid, accurate, and cost‐effective ...
Selen Dalgan, Qingshan Wei
wiley   +1 more source

Loss of NR2F6 Protects from Salmonella Typhimurium Infection

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk   +8 more
wiley   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo   +10 more
wiley   +1 more source

Importance and Characterisation of Concurrent Pathogens in Diarrhoeic Calves from North-Western Spain. [PDF]

open access: yesAnimals (Basel)
López-Novo C   +10 more
europepmc   +1 more source

The Multitarget Compound ZLY032 Achieves Treatment of Chronic Wounds

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
ZLY032, a dual free fatty acid receptor 1/peroxisome proliferator‐activated receptor δ agonist, accelerates wound healing in normal/diabetic/methicillin‐resistant Staphylococcus aureus‐infected models by promoting angiogenesis, reducing inflammation, and exhibiting antibacterial activity via argininosuccinate lyase targeting, with demonstrated efficacy
Manyu Gong   +27 more
wiley   +1 more source

Commensal Viruses Promote Intestinal Stem Cell Regeneration Following Radiation Damage by Inhibiting Hyperactivation of RIG‐I and Notch Signals

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
Ionizing radiation disrupts gut virome and bacteriome. Gut commensal viruses protect against intestinal damage and promote stem cell regeneration by inhibiting hyperactivation of RIG‐I and Notch signaling in stem cells. Fecal virome transplantation (FVT) from healthy donors can serve as a potential therapeutic intervention by enriching phages targeting
Xiaotong Zhao   +17 more
wiley   +1 more source

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