Results 271 to 280 of about 378,455 (346)

Akkermansia muciniphila‐Derived N‐Acetylspermidine Modulates the Localization of Intestinal α1,2‐Fucosylated Proteins to Maintain Gut Homeostasis

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This study demonstrates that Akkermansia muciniphila alleviates colitis by enhancing intestinal α1,2‐fucosylation through its metabolite N‐acetylspermidine. Mechanistically, N‐acetylspermidine‐induced PIM1 inhibition promotes HDAC2‐mediated reduction of chromatin accessibility at TP73, thereby upregulating C1GALT1C1 to boost α1,2‐fucosylation.
Ye Yao, Zhangming Pei, Yuanyuan Dai, Yinghan Chen, Zepeng Chang, Hongchao Wang, Jianxin Zhao, Hao Zhang, Qixiao Zhai, Wenwei Lu, Wei Chen   +10 more
wiley   +1 more source

Deficiency of cannabinoid receptors enhances host susceptibility to bacterial infection. [PDF]

mBio
Barker HA, Bhimani S, Tirado D, Canas JJ, Lemos LN, Roesch LFW, Ferraro MJ.   +6 more
europepmc   +1 more source

One‐Pot Isothermal Nucleic Acid Amplification Assisted CRISPR/Cas Detection Technology: Challenges, Strategies, and Perspectives

Advanced Science, Volume 12, Issue 37, October 6, 2025.
This review combines the current status of CRISPR (Clustered Regularly Interspaced Short Palindromic Repeat)‐based molecular diagnostic technology to expound the necessity and challenges faced in promoting the development of one‐pot detection. Besides, the focus is on a comprehensive summary and incisive analysis of emerging strategies for one‐pot ...
Hongyan Liu, Hui Yin, Leshan Xiu, Wenyu Wu, Qinqin Hu, Yingchen Xia, Brianna Garcia, Shamsuttiyeba Shifa, Hui Chen, Min Li, Kun Yin   +10 more
wiley   +1 more source

Molecular epidemiology of pESI-carrying <i>Salmonella</i> Infantis in Korea: insights from a one health framework. [PDF]

Emerg Microbes Infect
Kim Y, Cho H, Lee M, Jung SH, Chung YJ, Ko KS, Park KT.   +6 more
europepmc   +1 more source

In Situ Vaccines in the Era of Cancer Immunotherapy: Conceptual Innovation and Clinical Translation

Advanced Science, Volume 12, Issue 37, October 6, 2025.
In this review, the basic concepts of in situ vaccination are discussed, its advantages over conventional vaccines, and key historical milestones, from the first use of Coley's toxins to the most recent FDA‐approved in situ vaccine for bladder cancer.
Yiru Shi, Yuxuan Hou, Moustafa T. Mabrouk, Chengzhong Yu, Yannan Yang   +4 more
wiley   +1 more source

From Farm to Fork: Antimicrobial-Resistant Bacterial Pathogens in Livestock Production and the Food Chain. [PDF]

Vet Sci
Elbehiry A, Marzouk E.
europepmc   +1 more source

The Evolution of Functional Amyloids and Their Impact on Host–Microbe Interactions

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This review describes functional amyloids and highlights the importance of structural repetition and molecular mimicry that distinguish the amyloid fold. The authors describe how amyloid can be the last universal common ancestor of protein folds. The authors also discuss how microbes utilize functional amyloids and how the structural characteristics of
Divya Kolli, Saroj K. Rout, Roland Riek, Matthew R. Chapman   +3 more
wiley   +1 more source

Enhanced Genomic Surveillance Is Essential for Effective <i>Salmonella</i> Outbreak Response. [PDF]

China CDC Wkly
Wang Y, Xu X, Zhu B, Gao GF.
europepmc   +1 more source

Antimicrobial Peptides and Laying Hens Farming: A Review to Analyze the Improvement of the Animal Performance, Health, and Egg Quality. [PDF]

Scientifica (Cairo)
Brandão L, Leite WQ, Severino M, Sevilhano T, Pereira DF, Sartori D, Vicente EF.   +6 more
europepmc   +1 more source

First detection and genomic analysis of <i>mcr-1</i>-positive <i>Salmonella</i> Infantis isolated from a broiler production system in the United Arab Emirates. [PDF]

Front Vet Sci
Habib I, Mohamed MI, Lakshmi GB, Al Marzooqi HM, Afifi HS, Shehata MG, Elbediwi M.   +6 more
europepmc   +1 more source