Results 191 to 200 of about 99,967 (276)

Novel Animal Model of Enterobacteria Pathogenicity, Virulence, and Amoxicillin—Biosurfactant Synergic Using Nsombé (Rhynchophorus phoenicis Larvae)

open access: yesMicrobiologyOpen, Volume 14, Issue 4, August 2025.
This study highlights the potential of Rhynchophorus phoenicis larvae as an alternative infection model for evaluating host–pathogen interactions and the synergistic effects of combined antimicrobial therapies using antibiotics and biosurfactants. ABSTRACT Insect larvae are increasingly being employed as sophisticated infection models in the expanding ...
Sergy Patrick Junior Bissoko   +5 more
wiley   +1 more source

Ecotin protects Salmonella Typhimurium against the microbicidal activity of host proteases. [PDF]

open access: yesPLoS Pathog
Saposnik L   +11 more
europepmc   +1 more source

Analyzing the Challenges and Opportunities Associated With Harnessing New Antibiotics From the Fungal Microbiome

open access: yesMicrobiologyOpen, Volume 14, Issue 4, August 2025.
Graphical abstract illustrating the multifaceted approach to harnessing fungal microbiome diversity for antibiotic discovery. Key elements include historical insights, modern genomic tools, and innovative biotechnological strategies for isolating and enhancing fungal antibiotic production.
Md. Sakhawat Hossain   +5 more
wiley   +1 more source

Preclinical Evaluation of the Oral Toxicity, Genotoxicity, and Safety Pharmacology of LPM4870108, a Novel Potent Tropomyosin Receptor Kinase Inhibitor

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
Preclinical evaluation of the oral toxicity, genotoxicity, and safety pharmacology of LPM4870108. ABSTRACT Tropomyosin receptor kinase (Trk) inhibitors are an essential class of anticancer drugs treating NTRK gene fusions‐positive cancer. However, the potential for the emergence of on‐target resistance suggests newer Trk inhibitors with low drug ...
Xiaochen Zhang   +6 more
wiley   +1 more source

Modeling, virtual screening, and enzymatic docking of trehalose 6‐phosphate phosphatase and evaluation of the insecticidal effect of phthalimide, N‐(p‐tolylsulfonyl) on Aedes aegypti (Diptera: Culicidae)

open access: yesPest Management Science, Volume 81, Issue 8, Page 4777-4787, August 2025.
Schematic diagram of the experimental procedures used to perform the bioinformatic steps and insecticidal assays using trehalose 6‐phosphate phosphatase of Aedes aegypti and the molecule phthalimide, N‐(p‐tolylsulfonyl). Abstract BACKGROUND Aedes aegypti Linnaeus is a medically important vector because of its role in transmitting several arboviruses ...
Raquel Jemima Viana Lima   +3 more
wiley   +1 more source

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