Results 71 to 80 of about 378,356 (352)
Targeted Cancer Therapy Using Engineered Salmonella typhimurium
Obligate or facultative anaerobic bacteria such as Bifidobacterium, Clostridium, Salmonella, or Escherichia coli specifically colonize and proliferate inside tumor tissues and inhibit tumor growth.
Jin Hai Zheng, J. Min
semanticscholar +1 more source
Loss of NR2F6 Protects from Salmonella Typhimurium Infection
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk+8 more
wiley +1 more source
Background: Salmonella enterica serovar Typhimurium is one of the most important serovars of Salmonella enterica and is associated with human salmonellosis worldwide.
Reza Ranjbar+2 more
doaj
Whole-genome sequencing (WGS) is a valuable tool in research on foodborne pathogens. In this study, a total of 143 isolates of Salmonella serotypes Enteritidis, Typhimurium, and Heidelberg sourced from eggs and chickens were analyzed for their ...
Lijun Hu+6 more
doaj
Monoclonal Antibodies of a Diverse Isotype Induced by an O-Antigen Glycoconjugate Vaccine Mediate In Vitro and In Vivo Killing of African Invasive Nontyphoidal Salmonella. [PDF]
Nontyphoidal Salmonella (NTS), particularly Salmonella enterica serovars Typhimurium and Enteritidis, is responsible for a major global burden of invasive disease with high associated case-fatality rates.
core +1 more source
Salmonella Typhimurium is a major diarrheal pathogen and associated with invasive nontyphoid Salmonella (iNTS) disease in vulnerable populations.
A. Mather+31 more
semanticscholar +1 more source
Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou+8 more
wiley +1 more source
Host stress drives Salmonella recrudescence [PDF]
Host stress is well known to result in flare-ups of many bacterial, viral and parasitic infections. The mechanism by which host stress is exploited to increase pathogen loads, is poorly understood.
Bert, Wim+12 more
core +2 more sources
An Unstable Mutation in Salmonella typhimurium [PDF]
RECENTLY, Zamenhof et al. 1 described experiments which demonstrated the occurrence of pinpoint mutant colonies in Escherichia coli. These mutants arose in experiments in which 5-bromo-uracil was used as a mutagenic agent, and the pinpoint colonies were shown to be of three types: stable, unstable and very unstable.
openaire +3 more sources
Theranostic Toolbox for Neutrophil Functionalization
Here, neutrophil‐specific fluorine nanoparticles additionally equipped with either activating or inhibiting peptides for a background‐free 19F MRI‐based nanotheranostic approach are engineered. It is demonstrated that this approach is suitable to visualize and concomitantly direct neutrophil functionality depending on the specific requirements to ...
Pascal Bouvain+11 more
wiley +1 more source