Results 41 to 50 of about 8,623,469 (262)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Constitutive theory of geomaterials saturated with salt solution and its application in clay
The chemical activity of ions in salt solution will change the mechanical properties of saturated geomaterials, inducing geotechnical problems such as deterioration or even failure of engineering properties.
HU Yayuan , YUAN Shuhang
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
HYDROMETALLURGICAL METAL EXTRACTION FROM PCBs
There are many valuable metals hidden inside printed circuit boards (PCBs for short), such as copper, aluminum, lead, iron, tin, and even noble metals like gold, silver, and platinum. To be exact, approximately 49% of all metals in PCBs are copper, 21.8%
Гвідас ЙОКУБАУСКАС +3 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Molecular Dynamics Simulation of Membrane Distillation for Different Salt Solutions in Nanopores
Nanoporous membranes offer significant advantages in direct contact membrane distillation applications due to their high flux and strong resistance to wetting.
Jiadong Li +4 more
doaj +1 more source
The electrochemical corrosion characteristics of AZ31 and AZ61 magnesium alloys were analyzed in terms of potentiodynamic tests and electrochemical impedance spectroscopy. The influence of the solution composition and material surface finish was examined
J. Tkacz +6 more
semanticscholar +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source

