Results 21 to 30 of about 2,429,023 (353)

Pharmacological strategies in lung cancer-induced cachexia: effects on muscle proteolysis, autophagy, structure, and weakness [PDF]

open access: yes, 2014
Muscle wasting and cachexia are important systemic manifestations of highly prevalent conditions including cancer. Inflammation, oxidative stress, autophagy, ubiquitin-proteasome system, nuclear factor (NF)-kB, and mitogen activated protein kinases (MAPK)
Bal, Elisa Dora   +7 more
core   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Relación de revisores del año 2018

open access: yesRevista Peruana de Medicina Experimental y Salud Pública, 2018
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Rev Peru Med Exp Salud Publica, Instituto Nacional de Salud, Perú
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Valoración de los síntomas psicosomáticos relacionados con el estrés en las Academias de Formación Vial de la provincia de Alicante [PDF]

open access: yes, 2017
Se ha querido valorar el estrés en los aspectos fisiológicos que se genera en el profesor de Formación Vial, debido a que al desarrollar su trabajo necesariamente tiene un intercambio de información simultaneo con el medio, con el alumno, incluyendo ...
Cerdá Bañón, María Salud
core  

Ali Ferzat: From political cartoons in papers to political cartoons in digital media [PDF]

open access: yes, 2019
Ali Ferzat es uno de los caricaturistas más importantes del mundo árabe. Sus caricaturas empezaron como un acto comunicativo que pretendía reivindicar los derechos que no estaban contemplados dentro del mundo árabe. Así, se convirtieron en una válvula de
Flores Borjabad, Salud Adelaida
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Epistemological bases of the debate on linguistic sexism. [PDF]

open access: yes, 2016
En este trabajo analizamos los supuestos epistemológicos que subyacen a las diferentes posturas en torno del tema del sexismo lingüístico: la dicotomía lengua / habla; la independencia vs.
Márquez Guerrero, María Salud
core  

First time identification of Pandoraea sputorum from a patient with cystic fibrosis in Argentina: a case report [PDF]

open access: yes, 2017
Background: Pandoraea species are considered emerging pathogens in the context of cystic fibrosis (CF) and are difficult to identify by conventional biochemical methods. These multidrug resistant bacteria remain poorly understood particularly in terms of
Alvarez, Florencia   +11 more
core   +2 more sources

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

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