Results 21 to 30 of about 41,152 (290)

“PPI? That sounds like Payment Protection Insurance”: Reflections and learning from a substance use and homelessness study Experts by Experience group

open access: yesResearch Involvement and Engagement, 2021
Plain English Summary This article describes the activities and lessons learned from the involvement of an Experts by Experience group in a National Institute for Health Research (NIHR) study.
Rebecca Foster   +7 more
doaj   +1 more source

What, How and Why of a Psychologically Informed Environment (PIE) Within Youth Refuge

open access: yesInternational Journal on Homelessness
Being homeless is broadly understood to be traumagenic. Thus, support services for individuals experiencing homelessness (such as youth refuge) are encouraged to use trauma-informed models of care.
Anda Jaman   +3 more
doaj   +1 more source

'I t’s not going to be a one size fits all': a qualitative exploration of the potential utility of three drug checking service models in Scotland

open access: yesHarm Reduction Journal, 2023
Background Scotland currently has the highest rates of drug-related deaths in Europe, so drug checking services are being explored due to their potential role in reducing these deaths and related harms.
Hannah Carver   +14 more
doaj   +1 more source

Understanding Different Perspectives on Salvation

open access: yesEastern African Journal of Humanities and Social Sciences, 2023
Salvation is one of the widely bounded themes in the scripture that has gained traction under discourse due to the many perspectives under which it is viewed.
Chrispine Katiyi Banda
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Post-implementation Evaluation of a Digital Dictation System in a Large Health Service Using HOT-Fit Framework

open access: yesAsia Pacific Journal of Health Management, 2020
Objective: The objective of this study was to evaluate a digital dictation system (DDS) that has been implemented in a large health service. The data collected in this study was used to understand the overall uptake and performance of the system and ...
Christopher Bain   +3 more
doaj   +1 more source

What does Paul say about the scope of salvation in his epistle to the Romans? [PDF]

open access: yes, 2012
This study seeks to understand the argument for salvation in Romans and what meaning Paul intended for the reader. It will examine the different approaches to salvation, looking at exclusivism and its facets of justification by faith and the doctrine of ...
Henry, Joyphen C.
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

What constitutes effective problematic substance use treatment from the perspective of people who are homeless? A systematic review and meta-ethnography

open access: yesHarm Reduction Journal, 2020
Background People experiencing homelessness have higher rates of problematic substance use but difficulty engaging with treatment services. There is limited evidence regarding how problematic substance use treatment should be delivered for these ...
Hannah Carver   +3 more
doaj   +1 more source

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