Results 41 to 50 of about 77,794 (334)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Sacraments and symbols in the Salvation Army [PDF]

open access: yes, 1996
This work seeks to trace the attitude of The Salvation Army to sacraments and symbols from its early sacramental period (1865-1883) and then from 1883 to the present day, a longer time during which formal sacraments have not been used in Army worship ...
Lawson, Kenneth
core  

Health Information: Applications and challenges in the COVID-19 pandemic

open access: yesAsia Pacific Journal of Health Management, 2020
Global health systems are under immense pressure with the exponential growth and spread of COVID-19.  Public health and health system responses to the pandemic have relied on health information reporting, visualisation, and projections of incidence ...
Sheree Lloyd, Sue M Walker, Ani Goswami
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

National economic & social impact survey 2015 [PDF]

open access: yes, 2015
The results from the study reveal a bleak picture of entrenched and persistent poverty and disadvantage for a significant proportion of people who access Salvation Army ER and support services.
The Salvation Army
core  

RETRACTED: The impact of agricultural water salvation investment on economics development: Evidence from Eastern China.

open access: yesPLoS ONE, 2022
Agricultural water salvation is the lifeblood of the national economy and is of great significance to the high-quality development of the region. In order to maximize the economic assistances of agricultural water salvation investment, this article ...
Haofeng Lin   +6 more
doaj   +1 more source

The anorexia nervosa experience: Shame, Solitude and Salvation

open access: yes, 2017
Aim Women with anorexia are often perceived very negatively – for example, as manipulative and deceitful – both by wider society and treatment providers. In this context, it is important for practitioners to understand the experience of living with this
N. Rance, Victoria Clarke, N. Moller
semanticscholar   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Coming down the high road: Doing residential drug rehabilitation - Volume 1: A literature review on residential drug rehabilitation [PDF]

open access: yes, 2008
This project reflects The Salvation Army's desire to provide the 'best drug and alcohol treatment service in Tasmania' and develop policy, procedures, and practices that will assist residents.
White, Rob, Graham, Hannah
core  

Realist review of nature-based interventions for men: understanding the contexts and mechanisms necessary for successful outcomes

open access: yesBMC Public Health
Background Men face significant health disparities, including higher rates of premature death, mental health challenges, and substance use disorders. Nature-based interventions hold promise for improving men’s health and wellbeing by leveraging natural ...
Josh Dumbrell   +3 more
doaj   +1 more source

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