Results 101 to 110 of about 929,762 (263)

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Adapting tissue-engineered in vitro CNS models for high-throughput study of neurodegeneration [PDF]

, 2017
Neurodegenerative conditions remain difficult to treat, with the continuing failure to see therapeutic research successfully advance to clinical trials. One of the obstacles that must be overcome is to develop enhanced models of disease.
Cameron, GW, Drake, RA, Lee-Reeves, C, Loughlin, AJ, O'Rourke, C, Phillips, JB   +5 more
core   +3 more sources

Inhibition of FOXO3a/BIM signaling pathway contributes to the protective effect of salvianolic acid A against cerebral ischemia/reperfusion injury

Acta Pharmaceutica Sinica B, 2019
Salvianolic acid A (SalA) is an effective compound extracted from traditional Chinese medicine Salvia miltiorrhiza Bunge. The Forkhead box O3a (FOXO3a) signaling pathway plays crucial roles in the modulation of ischemia-induced cell apoptosis.
Junke Song, Wen Zhang, Jinhua Wang, Haiguang Yang, Qi-meng Zhou, Haigang Wang, Li Li, G. Du   +7 more
semanticscholar   +1 more source

Salvianolic acid A inhibits the growth of diffuse large B-cell lymphoma through MAPK pathways.

Experimental Hematology, 2020
Treatment options are limited in patients with diffuse large B-cell lymphoma (DLBCL). Salvianolic acid A (SAA) is a water-soluble phenolic acid extracted from Salvia miltiorrhiza (Danshen) with anti-tumor properties.
Shuting Li, Ji-wei Fang, T. Si, Ying Lu, Lei Jiang   +4 more
semanticscholar   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Rosmarinic Acid Derivatives’ Inhibition of Glycogen Synthase Kinase-3β Is the Pharmacological Basis of Kangen-Karyu in Alzheimer’s Disease

Molecules, 2018
Inhibition of glycogen synthase kinase 3β (GSK-3β) is considered to be the central therapeutic approach against Alzheimer’s disease (AD).
Pradeep Paudel, Su Hui Seong, Yajuan Zhou, Chan Hum Park, Takako Yokozawa, Hyun Ah Jung, Jae Sue Choi   +6 more
doaj   +1 more source

Experimental and theoretical assessment of salvianolic acid B, ellagic acid, and phorbol esters as drug candidates against breast and prostate cancer

Discover Chemistry
Global efforts to develop innovative anti-cancer lead compounds from natural compounds found in plants have gained advanced momentum, focusing on achieving Sustainable Development Goal (SDG) number 3 on good health and well-being.
Russell B. O. Ouma, Usama Raza, Silas M. Ngari, Joshua K. Kibet, Uzair Nisar, Muhammad Waqar Ali   +5 more
doaj   +1 more source

Electrospun Gelatin/OSA‐Starch Nanofibers for Encapsulation and Controlled Release of Sage Extract

Journal of Applied Polymer Science, Volume 143, Issue 15, April 15, 2026.
Schematic representation of electrospun gelatin/OSA‐starch nanofibers encapsulating sage extract, illustrating fabrication, nanofiber formation, and sustained antioxidant release. ABSTRACT In recent years, increasing research efforts have focused on assessing the potential of polymeric nanofibers to improve the bioavailability and stability of active ...
Rozhin Mohagheghian, Akram Pezeshki, Babak Ghanbarzadeh, Maryam Mohammadi, M. Ali Aboudzadeh   +4 more
wiley   +1 more source

Chemical characterization and bioactive properties of two aromatic plants: Calendula officinalis L. (flowers) and Mentha cervina L. (leaves) [PDF]

, 2016
The chemical composition and bioactive properties of two plants (Calendula officinalis L. and Mentha cervina L.) were studied. Their nutritional value revealed a high content of carbohydrates and low fat levels, and very similar energy values.
Barros, Lillian, Calhelha, Ricardo C., Castro, María Ángeles, Ferreira, Isabel C.F.R., Garcia, Pablo A., Miguel, María, Pereira, Carla, Santos-Buelga, Celestino   +7 more
core   +1 more source

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu, Junhong Yao, Jiaxin Deng, Minjie Zhou, Kaiyue Shen, Shishuo Sun, Xiaoge Gao, Qing Zhang, Haiheng Xu   +8 more
wiley   +1 more source