Results 51 to 60 of about 3,660 (215)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Contemporary Clinical Trials CommunicationsBackground: One recommendation for the allocation ratio between multiple drugs and a shared placebo control group in platform trials (PTs) is to use a k:1 allocation ratio for the placebo group relative to the drug group, where k is the number of drug ...
Yosuke Shimizu +3 more
doaj +1 more source
BMC Medical Research Methodology, 2019 Background Our work was motivated by the need to, given serum availability and/or financial resources, decide on which samples to test in a serum bank for different pathogens.
Stéphanie Blaizot +5 more
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
FEBS Open Bio, EarlyView.The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley +1 more source
Determination of the Optimal Stratum Boundaries in the Monthly Retail Trade Survey in the Croatian Bureau of Statistics [PDF]
Revista Română de Statistică, 2017 This paper aims to compare the current sample design of the Monthly Retail Trade Survey in the SAS environment and the sample design with generalized Lavallee-Hidiroglou method of strata construction in the R environment.
Ivana Jurina, Lidija Gligorova
doaj
The Sample Allocation Problem and Non-Uniform Compressive Sampling
CoRR, 2014 This paper discusses sample allocation problem (SAP) in frequency-domain Compressive Sampling (CS) of time-domain signals. An analysis that is relied on two fundamental CS principles; the Uniform Random Sampling (URS) and the Uncertainty Principle (UP), is presented. We show that CS on a single- and multi-band signals performs better if the URS is done
openaire +2 more sources
FEBS Open Bio, EarlyView.Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
MethodologyReplication is a core principle for research, and the recent recognition of the importance of constructing prediction intervals for precise replications highlights the need for robust sample-size planning methodologies.
Wei-Ming Luh, Jiin-Huarng Guo
doaj +1 more source