Results 51 to 60 of about 947,067 (264)

Data-Driven Sample Average Approximation with Covariate Information

, 2022
We study optimization for data-driven decision-making when we have observations of the uncertain parameters within the optimization model together with concurrent observations of covariates. Given a new covariate observation, the goal is to choose a decision that minimizes the expected cost conditioned on this observation.
Kannan, Rohit, Bayraksan, Guezin, Luedtke, James R.   +2 more
openaire   +3 more sources

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

A Multi- Objective Stochastic Programming Model for Power Capacity Planning with Sample Average Approximation Approach and Quantile Method [PDF]

چشم‌انداز مدیریت صنعتی, 2016
This paper, develop a linear stochastic programming model. The objective of model is planning for power energy capacity for facing with demand. In this model, capacity decisions are made to select the time, the location and the type of equipment for ...
Ezatollah Asgharizade, Ali Mohaghar, Naeimeh Taghavi   +2 more
doaj  

Sample average approximations in optimal control of uncertain systems

52nd IEEE Conference on Decision and Control, 2013
This paper focuses on an optimal control problem in which the objective is to minimize the expectation of a cost functional with stochastic parameters. The inclusion of the stochastic parameters in the objective raises new theoretical and computational challenges not present in a standard nonlinear optimal control problem.
Royset, Johannes O., Phelps, Chris, Gong, Qi   +2 more
openaire   +2 more sources

El método de aproximación por media muestral [PDF]

, 2018
The sample average approximation (SAA) method is an approach for solving stochastic optimization problems by using Monte Carlo simulation. The basic idea of such method is that we can approximate the expected objetive function by the corresponding sample
González López, Rafael
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The use of finite element method for simulation of heat conductivity processes in polar dielectrics irradiated by electron bunches [PDF]

Компьютерные исследования и моделирование, 2012
The paper describes the results of computer simulation of time-dependent temperature fields arising in polar dielectrics irradiated by focused electron bunches with average electron energy when analyzing with electron microscopy techniques.
Anna Gennadievna Maslovskaya, Anton Valerievich Sivunov   +1 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Strategic Placement and Sizing of Distributed Generation for Resilience Enhancement of Distribution Grids With Microgrid Formation

IEEE Access
The rise in frequency and severity of extreme weather events highlights the need for resilient power distribution networks. Microgrids can help improve the resilience of distribution grids by providing continuous power supply using local distribution ...
Dhiraj Pokhrel, Guodong Liu, Yang Chen, Hugh Medal   +3 more
doaj   +1 more source