Results 111 to 120 of about 25,776,776 (296)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

How well do the volunteers label land cover types in manual interpretation of remote sensing imagery?

International Journal of Digital Earth
High-quality samples for training and validation are crucial for land cover classification, especially in some complex scenarios. The reliability, representativeness, and generalizability of the sample set are important for further researches.
Yan Wang, Chenxi Li, Xueyi Liu, Hongdong Li, Zhiying Yao, Yuanyuan Zhao   +5 more
doaj   +1 more source

Probing dynamical symmetry breaking using quantum-entangled photons

, 2017
We present an input/output analysis of photon-correlation experiments whereby a quantum mechanically entangled bi-photon state interacts with a material sample placed in one arm of a Hong-Ou-Mandel (HOM) apparatus. We show that the output signal contains
Bittner, Eric R., Jerke, Jonathan, Kandada, Ajay Ram Srimath, Li, Hao, Piryatinski, Andrei, Silva, Carlos   +5 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Effect of magnetic viscosity on magnetic property measurements of hard magnetic materials

Стандартные образцы, 2018
Purpose. This paper is devoted to investing of the effect of magnetic viscosity on the results of measurements of the main hysteresis characteristics of hard magnetic alloys in an open magnetic circuit of vibrating sample magnetometer.Materials and ...
A. V. Perepelkina, E. A. Volegova, V. O. Vaskovskiy, A. S. Volegov   +3 more
doaj   +1 more source

Kapton charging characteristics: Effects of material thickness and electron-energy distribution [PDF]

, 1985
Charging characteristics of polyimide (Kapton) of varying thicknesses under irradiation by a very-low-curent-density electron beam, with the back surface of the sample grounded are reported.
Dulgeroff, C. R., Hymann, J., Viswanathan, R., Williamson, W. S.   +3 more
core   +1 more source

Scanning probe imaging of coexistent ferromagnetism and ferroelectricity at room temperature

, 2006
Room temperature coexistence of ferromagnetism and ferroelectricity in a thin film of a novel material of nominal composition PbTi0.5Fe0.5O3-d is probed by standard ferroelectric and ferromagnetic hysteresis loop measurements and by scanning probe ...
Bhattacharya, S., Gohil, S., John, J., Palkar, V. R., Purandare, S. C.   +4 more
core   +1 more source

Electron work function–a promising guiding parameter for material design

Scientific Reports, 2016
Using nickel added X70 steel as a sample material, we demonstrate that electron work function (EWF), which largely reflects the electron behavior of materials, could be used as a guide parameter for material modification or design.
Hao Lu, Z. Liu, X. Yan, Dongyang Li, L. Parent, H. Tian   +5 more
semanticscholar   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Material culture in Sixteenth Century Venice: a sample from probate inventories, 1510–1615 [PDF]

This paper presents a panel of data about material culture in early modern Venice. The data are taken from three samples of Venetian probate inventories drawn up voluntarily from Venetian widows in the years 1510–1615, at intervals of roughly fifty years.
Isabella Cecchini
core