Results 121 to 130 of about 2,783,159 (312)

Week 44 (10/26/20-11/01/20), Sample Collection

open access: yes, 2020
Documents relating to the Sample Collection phase of the OSIRIS-REx Asteroid Return Mission. Contains 4 files.This material is based upon work supported by NASA under Contract NNM10AA11C issued through the New Frontiers Program.OSIRIS-REx Mission records
OSIRIS-REx Asteroid Sample Return Mission
core  

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

High throughput preparation and analysis of plastically shaped material samples [PDF]

open access: yes, 2003
A rapid throughput method for the preparation, analysis or both of libraries of material samples is provided. According to the method, a plurality of samples is provided. The plurality of samples is then formed into a plurality of films.
Hajduk, Damian, Kolosov, Oleg
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Marco Polo: A Sample Return Mission to a Primitive NEO

open access: yes, 2008
This presentation was part of the session : Sample Return ChallengesSixth International Planetary Probe WorkshopMarco Polo is a Near-Earth Object (NEO) sample return mission currently studied by the European Space Agency (ESA).
Escorial, Diego   +10 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Conjugate CFD modeling for Multi-Sample drying of deformable porous food materials

open access: yesInternational Journal of Thermofluids
Drying of deformable porous materials (DPMs) involves complex coupling of heat transfer, moisture migration, and structural deformation, which are often oversimplified in conventional models.
Mohammad U.H. Joardder   +3 more
doaj   +1 more source

Pré-Tratamento para Amostras de Concreto, Atum, Material Refratário e Argilas para as análises de cloreto, sódio, silica e metais respectivamente [PDF]

open access: yes, 2001
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Curso de Química.Grande parte das principais metodologias empregadas em nossos estudos foram dedicadas aos métodos de pré-tratamento que transformam ...
Martins, Renata Fátima
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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