Results 51 to 60 of about 214,630 (306)
Sample Path Properties of Stochastic Processes Represented as Multiple Stable Integrals [PDF]
, 1989 Sample Path Properties of Stochastic Processes Represented as Multiple Stable ...
Taqqu, M. S. +2 more
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
npj Biofilms and Microbiomes, 2022 Operational factors and microbial interactions affect the ecology in anaerobic digestion systems. From 12 lab-scale reactors operated under distinct engineering conditions, bacterial communities were found driven by temperature, while archaeal ...
Bing Guo +7 more
doaj +1 more source
Journal of Materials Research and Technology, 2021 This study aimed to determine the contribution of B2O3/CdO substitution on gamma-ray attenuation behaviors of 46V2O5–46P2O5–(8−x)B2O3–xCdO (x = 0–8 mol%) glass system.
H.O. Tekin +8 more
doaj +1 more source
Sample Path Properties of Generalized Random Sheets with Operator Scaling [PDF]
Journal of Theoretical Probability, 2020 AbstractWe consider operator scaling $$\alpha $$ α -stable random sheets, which were introduced in Hoffmann (Operator scaling stable random sheets with application to binary mixtures. Dissertation Universität Siegen, 2011). The idea behind such fields is to combine the properties of operator scaling $$\alpha $$
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Investigation of advanced strain-path dependent material models for sheet metal forming simulations [PDF]
, 2006 Sheet metal forming processes often involve complex loading sequences. To improve the prediction of some undesirable phenomena, such as springback, physical behavior models should be considered.
BALAN, Tudor +5 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source