Results 231 to 240 of about 7,654,949 (307)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Non-decalcified human teeth sample preparation method for MALDI mass spectrometry imaging. [PDF]

Anal Chim Acta
Bender KJ, Spurgeon JE, Zhai CY, Arora M, Neumann EK.   +4 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Evaluation of sample preparation methods for NMR-based metabolomics of Atlantic salmon (Salmo salar) ovarian fluid. [PDF]

Fish Physiol Biochem
Casu F, Bayless AL, Peterson BC, Hamlin HJ, Boggs ASP, Schock TB.   +5 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

A practical guide to sample preparation for immunoprecipitation coupled with mass spectrometry analysis of <i>C. elegans</i> proteins. [PDF]

MicroPubl Biol
Wang JH, Dong MQ.
europepmc   +1 more source

An efficient clear-native PAGE-based workflow for cryo-electron microscopy sample preparation of large protein complexes. [PDF]

Plant Methods
Yang Z, Kameo S, Seki S, Kurisu G, Tanaka R, Kawamoto A, Takabayashi A.   +6 more
europepmc   +1 more source

Protocol for metabolite extraction and sample preparation from primary astrocytes for mass spectrometry-based metabolomic analysis. [PDF]

STAR Protoc
Chang YG, Lin GM, Lin CY, Chern Y.
europepmc   +1 more source

Investigation of Sample Preparation Methods of Dietary Supplements for Total Selenium Determination. [PDF]

ACS Omega
Oliveira LMA, Moraes DP, Pereira JSF.
europepmc   +1 more source

Analytical Methodologies for Benzo[a]pyrene in Foods: A Review of Advances in Sample Preparation and Detection Techniques. [PDF]

Foods
Yuan D, Zhang S, Hong B, Shan S, Zhang J, Wu Q, Sha D, Lu S, Ren C.   +8 more
europepmc   +1 more source