Results 261 to 270 of about 15,581,970 (330)

Sample Preparation for Multi-Omics Analysis: Considerations and Guidance for Identifying the Ideal Workflow. [PDF]

Proteomics
Woodland B, Farrell LA, Brockbals L, Rezcallah M, Brennan A, Sunnucks EJ, Gould ST, Stanczak AM, O'Rourke MB, Padula MP.   +9 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Evaluation of Three Sample Preparation Methods for LC-HRMS Suspect Screening of Contaminants of Emerging Concern in Effluent Wastewater. [PDF]

Anal Chem
Orlando-Véliz D, Bonansea RI, García-Vara M, Nikolopoulou V, López de Alda M.   +4 more
europepmc   +1 more source

Esterification of Cyclic N⁶‐Threonylcarbamoyladenosine During RNA Sample Preparation [PDF]

Larissa Bessler, Jason Sirleaf, Christopher J. Kampf, Katarzyna Debiec, Grażyna Leszczyńska, Till Opatz, Mark Helm   +6 more
openalex   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

A modified sample preparation strategy combined with UHPLC-MS/MS for simultaneous determination of 147 pesticides and related compounds in vegetables and fruits. [PDF]

Food Chem X
Wen G, Wang T, Zhao L, Si W, Tang H, Dong M, Zhao Y, Wang W.   +7 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Supplementary Information: A Taguchi Design of Experiments Approach for Untargeted Metabolomics Sample Preparation Optimization. [PDF]

J Biomol Tech
Garcia BM, Gouveia GJ, Shaver AO, Borges RM, Amster IJ, Edison AS, Iii FEL.   +6 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Sample Preparation for MALDI-TOF Mass Spectrometry of Model Prebiotic Reactions in Simulated Ocean World Environments. [PDF]

ACS Omega
Dzurilla KA, Herndon EC, Barge LM, Forsythe JG.   +3 more
europepmc   +1 more source