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Basic Statistical Concepts for Sample Size Estimation
For grant proposals the investigator has to include an estimation of sample size .The size of the sample should be adequate enough so that there is sufficient data to reliably answer the research question being addressed by the study.
Vithal K Dhulkhed+4 more
doaj
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg+2 more
wiley +1 more source
The Effect of Sample Size On (Cusum and ARIMA) Control Charts [PDF]
The purpose of this paper is to study Statistical Process Control (SPC) with a cumulative sum CUSUM chart which shows the total of deviations, of successive samples from the target value and the Average Run Length (ARL) is given quality level is the ...
Rashid, K. M. (Kawa)
core
Basic principles of sample size calculation
The calculation of sample size helps a medical researcher to assess cost, time, and feasibility of his project besides scientific justification and validity. Although frequently reported in journals, the details or the elements of sample size calculation
Shivam Pandey
doaj +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Nearly Optimal Sample Size in Hypothesis Testing for High-Dimensional Regression
We consider the problem of fitting the parameters of a high-dimensional linear regression model. In the regime where the number of parameters $p$ is comparable to or exceeds the sample size $n$, a successful approach uses an $\ell_1$-penalized least ...
Javanmard, Adel, Montanari, Andrea
core +1 more source
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Effective Sample Size for Importance Sampling based on discrepancy measures
The Effective Sample Size (ESS) is an important measure of efficiency of Monte Carlo methods such as Markov Chain Monte Carlo (MCMC) and Importance Sampling (IS) techniques.
Elvira, V., Louzada, F., Martino, L.
core +2 more sources
When designing any research project, definition is required of the sample size needed in order to carry out the study. This sample size is an estimate of the number of patients required in accordance with the pursued study objective. In this context, it is more efficient in terms of both cost and time to use samples than to work with the entire ...
AR González-Ramírez+1 more
openaire +3 more sources
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source