Results 81 to 90 of about 8,421,143 (315)
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source
Oral Oncology ReportsAn appropriate sampling technique with the exact determination of sample size involves a very vigorous selection process, which is actually vital for any empirical research.
Sirwan Khalid Ahmed
doaj
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Sample size for ophthalmology studies
Indian Journal of Ophthalmology, 2000 Knowledge and the usage of actual sample size formulae are a necessity as validity of the inferences from research studies is often dependent on this. This paper explains how sample sizes are calculated.
Naduvilath Thomas +2 more
doaj
Journal of Investigative Surgery, 1993 This paper sets forth the basic concepts of the calculation of sample size and power in clinical research. It provides the reader with a basic understanding of the relationship between sample size and power and the components within the research, such as the variability of the measure being used as the primary outcome. The paper also discusses a number
openaire +3 more sources
FEBS Letters, EarlyView.This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter +8 more
wiley +1 more source
Anchorage Community Survey 2007 Survey Sampling Design: Power and Sample Size [PDF]
, 2006 This working paper documents the power analysis, literature review, and precision considerations contemplated in designing the Anchorage Community Survey’s (ACS) 2007 sampling design.
Evans, Shel Llee
core +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source
Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase
FEBS Letters, EarlyView.The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu +5 more
wiley +1 more source
On bootstrap sample size in extreme value theory [PDF]
It has been known for a long time that for bootstrapping theprobability distribution of the maximum of a sample consistently,the bootstrap sample size needs to be of smaller order than theoriginal sample size. See Jun Shao and Dongsheng Tu (1995), Ex.3.9,
Geluk, J.L., Haan, L.F.M. de
core +1 more source