Results 91 to 100 of about 139,353 (284)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A DASP multiband spectrum sensing method based on total random sampling on Grid without replacement
, 2011 This paper proposes a method that deploys nonuniform sampling and spectral analysis to perform reliable spectrum sensing using sampling rates well below the ones demanded by uniform-sampling-based DSP.
Tarczynski, A., Al-Ani, M., Ahmad, B.I.
core
Card guessing and the birthday problem for sampling without replacement
, 2021 Consider a uniformly random deck consisting of cards labelled by numbers from $1$ through $n$, possibly with repeats. A guesser guesses the top card, after which it is revealed and removed and the game continues.
Ottolini, Andrea, He, Jimmy
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Non-uniform coverage estimators for distance sampling.
, 2009 Previously in the University eprints HAIRST pilot service at http://eprints.st-andrews.ac.uk/archive/00000445/Allocation of sampling effort in the context of distance sampling is considered.
Rexstad, Eric
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
A Comparison of Model-Assisted Estimators to Infer Land Cover/Use Class Area Using Satellite Imagery
Remote Sensing, 2014 Remote sensing provides timely, economic, and objective data over a large area and has become the main data source for land cover/use area estimation. However, the classification results cannot be directly used to calculate the area of a given land cover/
Yizhan Li +5 more
doaj +1 more source
On the two-phase framework for joint model and design-based inference [PDF]
We establish a mathematical framework that formally validates the two-phase “superpopulation viewpoint” proposed by Hartley and Sielken (1975), by defining a product probability space which includes both the design space and the model space. We develop a
Ioana Schiopu Kratina +1 more
core