Results 31 to 40 of about 2,279,602 (264)

Desafíos actuales frente a la medición de la reputación corporativa

open access: yesAustral Comunicación, 2013
Hay un acuerdo entre los investigadores acerca de que la reputación corporativa es uno de los más valiosos activos intangibles en toda organización (en el presente estudio los términos reputación y reputación corporativa se emplearán indistintamente ...
Domingo Sanna
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Reseña de "El elogio a los Libertadores. Presencia de José de San Martín y Simón Bolívar en la Universidad de San Marcos de Lima", de Ricardo Pinto-Bazurco Mendoza (compilación y prólogo)

open access: yesRiqch'ariy, 2021
Entre la cantidad de publicaciones enfocadas en la temática del bicentenario de la independencia y nacimiento de la república peruana, se presentan también algunas que transcriben documentos de tan interesante coyuntura.
Roberto Ojeda Escalante
doaj  

Spinal Accessory Nerve Duplication – A Rare Anatomical Consternation During Neck Dissectio

open access: yesAsian Pacific Journal of Cancer Care, 2021
Prevention of the spinal accessory nerve (SAN) is an indispensable aspect of the functional neck dissection surgery to avoid highly disabling shoulder syndrome postoperatively.
Rohit Jindal   +6 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Propuestas y estrategias para la protección y promoción del desarrollo de drogas huérfanas

open access: yesRevista Iberoamericana de la Propiedad Intelectual
El objeto de este trabajo es brindar propuestas y estrategias para incentivar el desarrollo de este tipo de medicamentos. Las propuestas consisten en la integración entre la exclusividad regulatoria y la protección por patentes, dado que los diversos ...
Angela Santorsa Gutierrez
doaj   +1 more source

Deep learning‐based identification of sinoatrial node‐like pacemaker cells from SHOX2/HCN4 double‐positive cells differentiated from human iPS cells

open access: yesJournal of Arrhythmia, 2023
Background Cardiomyocytes derived from human iPS cells (hiPSCs) include cells showing SAN‐ and non‐SAN‐type spontaneous APs. Objectives To examine whether the deep learning technology could identify hiPSC‐derived SAN‐like cells showing SAN‐type‐APs by ...
Takayuki Wakimizu   +6 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Privacidad, huella digital y derecho a la protección de datos personales en Internet

open access: yesRevista Internacional de Derechos Humanos
Este artículo examina los derechos relacionados con la privacidad y la protección de datos personales mediante el adecuado manejo de nuestra huella digital, una identidad en línea de la cual resulta inevitable escapar, dado que muchas de las actividades ...
María Fernanda Sánchez Díaz
doaj   +1 more source

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