Results 41 to 50 of about 3,325,360 (317)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Tratamiento de la colusión en la contratación pública: una visión del caso colombiano

open access: yesRevista de Derecho, 2014
La colusión, entendida como un pacto ilícito en daño a tercero, la cual se da en los procesos de contratación pública, es un acuerdo anticompetitivo sancionado por el numeral 9 del artículo 47 del Decreto 2153 de 1992, y más recientemente por la Ley 1474
Camilo Ernesto Ossa Bocanegra
doaj  

Reseña de "El elogio a los Libertadores. Presencia de José de San Martín y Simón Bolívar en la Universidad de San Marcos de Lima", de Ricardo Pinto-Bazurco Mendoza (compilación y prólogo)

open access: yesRiqch'ariy, 2021
Entre la cantidad de publicaciones enfocadas en la temática del bicentenario de la independencia y nacimiento de la república peruana, se presentan también algunas que transcriben documentos de tan interesante coyuntura.
Roberto Ojeda Escalante
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Rules for the government of public schools of San Antonio, Texas, as revised and adopted by the San Antonio School Board, August, 1913

open access: yes, 1913
Course of study for the public schools of San Antonio, Texas, for the 1913-1914 school year. The books lists textbooks and other materials that should be used in the San Antonio public schools.
San Antonio Independent School District (Texas)
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Synthesis and properties of novel styrene acrylonitrile/polypropylene blends with enhanced toughness

open access: yesChemistry Central Journal, 2018
Background Although polypropylene (PP) has been widely used, its brittleness restricts even further applications. Methods In this study, we have used a melt blending process to synthesize styrene acrylonitrile (SAN)/PP blends containing 0, 5, 10, 15 and ...
Yi-jun Liao, Xiao-li Wu, Lin Zhu, Tao Yi
doaj   +1 more source

La cláusula penal abusiva y el requisito de la desproporción de la pena

open access: yesRevista Jurídica Austral, 2020
Se analiza el requisito central del cual depende si una cláusula penal es o no abusiva (y, por ende, si debe o no ser reducida): su desproporción. A este efecto, debe dilucidarse si es proporcionada con el valor de la prestación o del resarcimiento que ...
Andrés Sánchez Herrero
doaj   +1 more source

Percepción de los estudiantes de Fonoaudiología de la Universidad San Sebastián sobre la simulación clínica con paciente estandarizado

open access: yes, 2018
Magíster en Educación en Ciencias de la SaludIntroducción: La simulación clínica con paciente estandarizado es una metodología utilizada en la actualidad durante el proceso de enseñanza-aprendizaje, provee un ambiente seguro donde el estudiante tiene la ...
San Juan Cortés, Hugo   +1 more
core  

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