Results 91 to 100 of about 49,451 (306)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Self-Organization for Collective Action: An Experimental Study of Voting on Formal, Informal, and No Sanction Regimes [PDF]

open access: yes
Entrusting the power to punish to a central authority is a hallmark of civilization. We study a collective action dilemma in which self-interest should produce a sub-optimal outcome absent sanctions for non-cooperation.
Louis Putterman   +2 more
core  

Sanctioning the sanctioned : A postcolonial perspective on the sanctions paradox

open access: yes, 2020
The aim of this is to develop a theoretical framework for addressing the usage and effects of economic sanctions, through a postcolonial perspective on the human rights discourse, by examining how economic sanctions can be legitimized even though proven to be ineffective and harmful to civilians.
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Guide de gestion de la sanction des études secondaires en formation générale des jeunes

open access: yes, 1996
1995/1996-Version française publ.
Québec (Province). Direction de la sanction des études
core  

CONTENT OF LEGAL NORMS’ SANCTIONS IN INFORMATION-PSYCHOLOGICAL APPROACH TO THE RESEARCH OF LEGAL PHENOMENA

open access: yesRussian Journal of Economics and Law, 2013
Objective: to reveal the connections between the conventional public values and the content of legal norms’ sanctions by comparative research. Methods: formal-legal, comparative-legal, systemic-structural and axiological.
A. V. Krasnov
doaj  

Anti-sanction and sanction economic policy of Russia in 2022–2025. Part 3: analysis of anti-crisis measures, managing Russian sanctions and anti-sanctions

open access: yesRussian Journal of Economics and Law
Objective: to propose anti-sanction and sanction measures based on the analysis of the external and internal environment of the Russian economy and anti-crisis measures implemented by the Russian government.Methods: techniques of abstract-logical method ...
D. V. Manushin
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Guide de gestion de la sanction des études secondaires en formation générale des jeunes /

open access: yes, 1984
1984?
Québec (Province). Direction de la sanction des études
core  

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