From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Guide de gestion de la sanction des études en formation professionnelle -- /
, 1993 1993
Québec (Province). Direction de la sanction des études
core +1 more source
Russian Journal of Economics and LawObjective: to propose anti-sanction and sanction measures based on the analysis of the external and internal environment of the Russian economy and anti-crisis measures implemented by the Russian government.Methods: techniques of abstract-logical method ...
D. V. Manushin
doaj +1 more source
Evaluation of Vulnerability of Iranian Economic Sectors due to International Sanctions: Mixed Variable Input-Output Approach [PDF]
Faslnāmah-i Pizhūhish/Nāmah-i Iqtisādī, 2015 Resilience economy as a new subject is considered for Iranian economic policies since 2013. Applying mainstream economic theories for solving economic issues in Iran is the main concern of general policies on resilience economy.
Ali Faridzad, Habib Morovvat
doaj
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Self-Organization for Collective Action: An Experimental Study of Voting on Formal, Informal, and No Sanction Regimes [PDF]
Entrusting the power to punish to a central authority is a hallmark of civilization. We study a collective action dilemma in which self-interest should produce a sub-optimal outcome absent sanctions for non-cooperation.
Louis Putterman +2 more
core
The function of imperial sanction and ministerial countersignature in Austrian legislation 1861-1918
Journal on European History of Law, 2012 From 1861 to the end of the Austro-Hungarian monarchy two things were necessary to enact a new law: an act of parliament and the sanction by the emperor. Before a new law was published it had to be countersigned at least one minister.
Christoph Schmetterer
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source