Results 101 to 110 of about 49,451 (306)
SANCTIONS OF PROHIBITING LEGAL NORMS: NOVELTIES IN LEGAL REGULATION
Russian Journal of Economics and Law, 2014 Objective: identifying changes within the legal regulation of social relations through sanctions of prohibiting legal norms. Methods: formal-legal and comparative legal.
N. N. Rybushkin, A. V. Krasnov
doaj
Вестник Северо-Кавказского федерального университета, 2022 In this work the sources of information and methods allowing to determine an investment potential of the country at the regional level that allows to give the quality characteristic to each subject of the country and effectively to distribute investment ...
Irina Solovyova, Oksana Takhumova
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Modalités d'application de la politique de sanction des études secondaires professionnelles /
, 1987 Comprend un ...
Québec (Province). Direction de la sanction des études
core
THE MEANING OF A LEGAL CATEGORY OF “SANCTION”
Russian Journal of Economics and Law, 2015 Objective: to study the legal category of sanction. Methods: dialectical, systematic, and logical methods of analysis, synthesis. Results: the study of the legal category of "sanction" has shown that a sanction can be applied on a regulatory or ...
A. S. Panova
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Guide de gestion de la sanction des études en formation professionnelle -- /
, 1993 1993
Québec (Province). Direction de la sanction des études
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
criminal sanction disciplinary sanction
, 2014 Deux thèses s’affrontent concernant les liens qu’entretiennent la sanction pénale et la sanction disciplinaire. Une première conception considère que la sanction disciplinaire est distincte de la sanction pénale.
Koukezian, Thomas
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source