Results 151 to 160 of about 64,771 (293)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Program Evaluation : Social Studies : Elementary Cycle Two

open access: yes, 1993
Québec (Province). Direction de la sanction des études
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Implementation of Sanctions

open access: yes, 2019
This chapter aims to provide an overview of Japanese approaches to economic sanctions by addressing both their legal and political backgrounds and their transitions. Until the beginning of the twenty-first century, the Japanese government approached economic sanctions from the perspective of international cooperation. Japan has been reluctant to impose
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Professional sanction in business criminal law : a contribution to a general theory of sanction

open access: yes, 2012
Le sujet par son intitulé "la sanction professionnelle en droit pénal des affaires" évoque à chacun l'idée que la sanction professionnelle serait la sanction applicable en droit pénal des affaires.
Baldes, Olivia
core  

From violation to stigma: a literature review of athletes' lived experiences following anti-doping sanctions. [PDF]

open access: yesFront Sports Act Living
Lockett I   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy