Results 41 to 50 of about 424,132 (308)

Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek, Lori Wiener, Stephanie Veldhuijzen van Zanten, Donna Johnston, Fyeza Hasan, Adam Rapoport, Nathasha Datoo, Kimberley Widger, Sumit Gupta, Karen Fergus, Anthony K. C. Chan, Alisha Kassam, Emily McCullogh, Dave Lysecki   +13 more
wiley   +1 more source

Nonproliferation economic sanctions in US foreign policy: political and juridical aspects

Vestnik RUDN. International Relations, 2014
Economic sanctions, an age-old tool of statecraft, are becoming increasingly central to shaping strategic outcomes. In the post-Cold War economic sanctions have become virtually the default option in US foreign policy.
Y A Sedlyar
doaj  

SANCTIONS POLICY IN THE INDONESIAN ACT. NO. 35 OF 2009 ON NARCOTICS

Jurnal Pembaharuan Hukum, 2018
Law is a legitimate product that is issued by the government / state is defined as a rule that should be known by the people or the public anywhere in the territory.
Indah Setyowati
doaj   +1 more source

International Economic Sanctions: Improving the Haphazard U.S. Legal Regime [PDF]

, 1999
The United States has resorted increasingly to economic sanctions as a major tool in its foreign policy. Recent targets include Panama, South Africa, Nicaragua, Libya, the Soviet Union, Poland, and Iran.
Carter, Barry E.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

THE IMPACT OF SANCTIONS POLICY ON ECONOMIC ACTIVITY AND ENTERPRISE SECURITY: PROBLEMS OF LEGAL REGULATION AND MANAGEMENT TOOLS IN A STATE OF WAR

Фінансово-кредитна діяльність: проблеми теорії та практики
The purpose of this article is to conduct a comprehensive study of sanctions policy as an instrument of state regulation in conditions of martial law by analyzing the current regulatory legal framework that determines the procedure for imposing and ...
Марія Бліхар, Ольга Пацула, Наталія Шевченко, Ярина Теслюк, Степан Васьків   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

The Influence of Local Wisdom in Effective Forest Protection Policy Based on Legal Norms [PDF]

E3S Web of Conferences
This study explores factors impacting the effectiveness of forest protection policies in Indonesia, focusing on legal regulatory norms. Field findings reveal that community members continue cutting down trees due to economic need and limited awareness of
Handitya Binov, Sacipto Rian, Wahab Harlida Abdul, Malim Dinna Danaya LaOdde   +3 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Implementation of EU sanctions against Belarus

Старожитності Лукоморʼя
Sanctions are one of the most important approaches to resolving international conflicts, influencing regime change in a country and promoting democracy, peace and stability in the region.
Liudmyla Vovchuk, Andrii Volkivskyi
doaj   +1 more source