Results 71 to 80 of about 15,179 (253)

Leishmania donovani's protein tyrosine phosphatases interact with DUF21 and respond to environmental magnesium

The FEBS Journal, Volume 293, Issue 6, Page 1754-1770, March 2026.
The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini, Hira Khursheed, Wen Wei Zhang, Isabelle Aubry, Greg Matlashewski, Michel L. Tremblay, Patrick Lypaczewski   +6 more
wiley   +1 more source

Ecology of cutaneous leishmaniasis in Sinai: linking parasites, vectors and hosts

Memorias do Instituto Oswaldo Cruz, 2014
Cutaneous leishmaniasis (CL) is a neglected clinical form of public health importance that is quite prevalent in the northern and eastern parts of Egypt.
Abdallah Mohammed Samy, Said Abdallah Doha, Mohamed Amin Kenawy   +2 more
doaj   +1 more source

A Proposed Framework for Effective Implementation of Quality Management Within Training

International Journal of Training and Development, Volume 30, Issue 1, Page 51-67, March 2026.
ABSTRACT Quality management (QM), a holistic approach incorporating managerial processes, is necessary for effective organisational processes, including training. This study investigates leaders' perceptions, attitudes, and commitment to quality training management within corps training units (CTUs) in the South African Army.
Renier (RC) Els, Helen (HW) Meyer
wiley   +1 more source

A systematic review and meta-analysis of the prevalence of Leishmania infantum in sandflies in Iran

Asian Pacific Journal of Tropical Medicine
Objective: To determine the overall and pooled prevalence of Leishmania (L.) infantum in sandfly vectors in Iran. Methods: The present research conducted a systematic review and meta-analysis and searched regional databases such as PubMed, Scopus, Web of
Sara Rahimi, Homa Arshadi, Hamid Reza Shoraka, Aioub Sofizadeh, Arman Latifi   +4 more
doaj   +1 more source

Leishmania-sandfly interactions [PDF]

Open Journal of Tropical Medicine, 2018
There is a specific association between insect vector species and parasites [1]. The susceptibility or resistance of a species of sandfly to the development of a particular parasite depends on its ability to overcome certain barriers such as the proteolytic enzymes of the midgut, the peritrophic membrane surrounding the blood meal, and excretion of the
openaire   +1 more source

Monodentate Phosphine Modulation in Cyclometallated Platinum(II) Complexes for Antileishmanial, Antiviral, and Antitumor Applications

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto, Gustavo Clauss, Jennyfer Castro, Marcus S. A. Garcia, Natasha M. Cassani, Bruna C. Sandim, Ana Laura C. Oliveira, Stephanie P. B. Reyes, Nádija N. P. da Silva, Fillipe V. Rocha, Ana C. G. Jardim, Danilo C. Miguel, Camilla Abbehausen   +12 more
wiley   +1 more source

Global distribution maps of the leishmaniases [PDF]

, 2014
The leishmaniases are vector-borne diseases that have a broad global distribution throughout much of the Americas, Africa, and Asia. Despite representing a significant public health burden, our understanding of the global distribution of the ...
Alvar, Ashford, Balk, Banuls, Barbet-Massin, Benkova, Bern, Bern, Bhatt, Bhunia, Bhunia, Boelaert, Brady, Branco, Cardo, Chamaille, CIESIN/IFPRI/WB/CIAT, Cross, de Oliveira, De'ath, Dedet, Desjeux, Edberg, Elith, Elith, Elnaiem, Elnaiem, FAO, Feliciangeli, Fernandez, Fischer, Fleiss, Freifeld, Friedman, Galvez, Gebre-Michael, Gonzalez, Gonzalez, Guzman, Harhay, Hartemink, Hay, Hay, Herrero, Hijmans, Hlavacova, Hutchinson, Ives, Kasap, Killick-Kendrick, Lima, Lozano, Malafaia, Malaviya, Murray, Murray, Nordhaus, Nordhaus, Novais, Peterson, Peterson, Phillips, Phillips, Poche, Ready, Reithinger, Reithinger, Reithinger, Rogers, Scharlemann, SINAN, Singh, Sinka, Sinka, Sinka, Syfert, Thomson, Toumi, Uranw, Van Der Wal, WHO, WHO, WHO, Zeilhofer   +83 more
core   +7 more sources

Toward Dual‐Function Nanoparticle Platforms for Arboviral Diagnostics and Vaccines: Advances, Challenges, and Future Prospects

Nano Select, Volume 7, Issue 2, February 2026.
This review explores nanoparticle (NP)‐based biosensors and nanovaccine platforms for arboviral infections, highlighting their design, performance, and translational potential. By comparing case studies across viruses, it identifies gold‐standard nanomaterials such as gold NPs (AuNPs), zinc oxide NPs (ZnONPs), molybdenum disulfide (MoS2) nanocomposites,
Peyman Halvaeikhanekahdani, Sajad Zandi, Qadeer Ahmad, Hadiseh Payravand   +3 more
wiley   +1 more source

The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulation.

, 2010
OBJECTIVE: Elevated serum levels of the acute-phase protein serum amyloid A (SAA) are a marker for active rheumatoid arthritis (RA), and SAA can also be found in the tissues of patients with active RA.
Björkman, Lena, Bylund, Johan, Dahlgren, Claes, Karlsson, Anna, Raynes, John G, Shah, Chandrabala   +5 more
core   +1 more source

Properties and Limitations of eDNA Substrates for Terrestrial Animal Monitoring

Molecular Ecology Resources, Volume 26, Issue 2, February 2026.
ABSTRACT Environmental DNA (eDNA) constitutes a valuable tool for monitoring terrestrial animal diversity, but outcomes are affected by multiple factors. Among these factors, the choice of sampling substrate and method is especially important and must be aligned with research objectives.
Beilun Zhao, Tobias Andermann
wiley   +1 more source