Results 11 to 20 of about 324,806 (229)

Dengue, chikungunya and Zika virus surveillance in blood donors in Brazil, 2019-2021. [PDF]

Vox Sang
Abstract Background and Objectives Arbovirus infections are a major public health concern in Brazil and an ongoing blood safety concern. Periodic outbreaks of such infections are common in the general population. This study aimed to establish the rates of dengue, chikungunya and Zika virus (DENV, CHIKV, ZIKV) RNAemia among blood donors at six public ...
Grebe E, Buccheri R, Montalvo L, Kashima S, Miranda C, Milani P, Stone M, Livezey K, Capuani L, Alencar CS, Amorim L, Loureiro P, Ribeiro M, da Costa AG, Mendrone A, Busch MP, Sabino EC, Custer B, Recipient Epidemiology and Donor Evaluation Study‐IV‐Pediatric (REDS‐IV‐P) Brazil.   +18 more
europepmc   +2 more sources

Zika virus surveillance post-epidemic in blood donors from São Paulo, Brazil 2016-2020. [PDF]

Transfus Med
Abstract Introduction Zika virus (ZIKV) is primarily transmitted through the bite of the Aedes aegypti mosquito, though transmission via blood transfusion has also been documented. During the 2015 ZIKV epidemic in Brazil, severe complications were observed in pregnant women, leading to fetal microcephaly. This study evaluated the persistence of ZIKV in
Ferreira SC, Levi JE, Nishiya AS, de Almeida-Neto C, Ferreira JE, Derriga J, Salles NA, Polato SPG, Dantas KC, Boturão-Neto E, Rocha MM, Rocha V, Mendrone-Jr A.   +12 more
europepmc   +2 more sources

Metformin Downregulates the STAT Pathway and Reduces Bone Marrow Fibrosis in Primary Myelofibrosis Patients: Final Results of the Phase II FIBROMET Trial. [PDF]

Hematol Oncol
ABSTRACT Primary myelofibrosis (PMF) is a chronic myeloproliferative neoplasm characterized by the activation of the JAK‐STAT pathway. Previous evidence showed that metformin might be a possible therapeutic option for treating JAK2‐mediated myeloproliferative neoplasms.
Melo Campos P, Pagnano KBB, Niemann FS, Mancuso RI, Della Via FI, Congrains A, Coelho-Silva JL, Tinoco ÂC, Assis-Mendonça GR, Freitas LLL, Traina F, Saad STO.   +11 more
europepmc   +2 more sources

Assessment of Leishmania exposure in blood donors from a non-endemic urban area: A study in São Paulo. [PDF]

Vox Sang
Abstract Background and Objectives According to the World Health Organization, more than 1 billion people are at risk of leishmaniasis in over 89 countries. Environmental changes such as deforestation, urban expansion and climate change facilitate the spread of sand fly vectors and reservoirs, increasing disease transmission.
de Lima IS, Ferreira SC, Nishiya AS, Kesper N, Ferreira JE, de Castro Gomes CM, Derriga J, Dantas KC, Polato SPG, Salles NA, Lindoso JAL, Fanciani T, de Almeida-Neto C, Rocha V, Mendrone A.   +14 more
europepmc   +2 more sources

UTILIZAÇÃO DE TÉCNICAS SOROLÓGIAS ADICIONAIS PARA IDENTIFICAÇÃO DE ANTI-FY3

Hematology, Transfusion and Cell Therapy, 2021
Introdução: A correta identificação dos anticorpos irregulares é fundamental para encontrar concentrados de hemácias compatíveis para o receptor, garantir o suporte transfusional satisfatório e prevenir reações hemolíticas.
GF Devides, FSA Silva, F Latini, AJP Cortez, CP Arnoni, TAP Vendrame   +5 more
doaj   +1 more source

Selection and Characterisation of Minor Histocompatibility Antigen-Specific Regulatory T Cells in Fully HLA-Matched Setting for GVHD Therapy. [PDF]

Eur J Immunol
We optimised a protocol for mHA‐specific Treg (mTreg) selection in an HLA‐matched context while defining its phenotype, transcriptional state and function. mTreg were highly activated and exerted specific, HLA class II‐, contact‐dependent suppression. This protocol can be explored as a highly personalised antigen‐specific Treg‐based therapy in future ...
Pacini CP, Azevedo RI, Ramalhete L, Lainé HAJ, Soares MVD, Lacerda JF.   +5 more
europepmc   +2 more sources

SANGUE NAS FOLHAS, SANGUE NA RAIZ

EntreLetras, 2022
Luz em agosto, de William Faulkner, traz a história de um homem de pele branca com suposta ascendência negra perseguido após matar sua amante. Este trabalho se desdobrará na tentativa de versar sobre a aparição de alguns conceitos chaves em Luz em agosto, como a ideia de dupla consciência, conforme definido por W.E.B. Du Bois, e desumanização, partindo
Sergio Schargel, Brenda Rocha
openaire   +1 more source

The Italian Regulatory Guidelines for the implementation of Patient Blood Management [PDF]

, 2017
Comment in Towards the implementation of patient blood management across Europe.
Antonioli, Paola, Biancofiore, Gianni, Gentili, Sara, Liumbruno, Giancarlo M., Marano, Giuseppe, Pupella, Simonetta, Rafanelli, Daniela, Vaglio, Stefania, Velati, Claudio   +8 more
core   +1 more source

VALIDAÇÃO DO CONTADOR HEMATOLÓGICO SYSMEX XP300 NO LABORATÓRIO DE CONTROLE DE QUALIDADE DE HEMOCOMPONENTES – COLSAN

Hematology, Transfusion and Cell Therapy, 2023
Introdução: A análise celular através do contador hematológico Sysmex XP-300 na rotina do laboratório de controle de qualidade de hemocomponentes é utilizada como uma triagem para avaliar se as contagens plaquetárias (PLT), do concentrado de plaquetas ...
TG Sacramento, CP Melo, CB Costa, CP Arnoni, A Cortez, F Latini   +5 more
doaj   +1 more source

Gilteritinib in FLT3-mutated acute myeloid leukemia: A real-world Italian experience. [PDF]

Cancer
Abstract Background and Methods This real‐world study evaluated the clinical effectiveness of gilteritinib in 205 patients with relapsed or refractory (R/R) FLT3‐mutated acute myeloid leukemia (AML) enrolled in the Italian expanded access since January 2018.
Cairoli R, Del Castello L, Imbergamo S, Pierdomenico E, Papayannidis C, Borlenghi E, Vetro C, Chiusolo P, Fumagalli M, Minotti C, Marchesi F, Bernardi M, Musto P, Fracchiolla N, Candoni A, Lunghi M, Musso M, Guolo F, Mannina D, Lico A, Scattolin AM, Crugnola M, Galimberti S, Nadali G, Turrini M, Zappasodi P, Todisco E, Basilico C, Grillo G, Mancini V, Riva M, Bernasconi DP, Greco R.   +32 more
europepmc   +2 more sources