Results 161 to 170 of about 292,213 (250)

Longitudinal changes in circulating biomarkers from baseline to week 48 in treatment-Naïve people living with HIV initiating integrase inhibitor-based antiretroviral therapy. [PDF]

PLoS One
Blanco JR, Torralba M, Saumoy M, Alcaraz A, Del Amo MM, Olalla J, Dronda F, Boukichou-Abdelkader N, Bernal E, Padilla S, Peraire J, Artigues F, Bustinduy-Odriozola MJ, Iglesias HA, Delgado A, Imaz A, Pérez-Martinez L, Cohort CIS.   +17 more
europepmc   +1 more source

Evaluating Thiram‐Induced Embryotoxicity Using Integrated In Silico, In Vitro, and Transcriptomic Approaches

Environmental Toxicology, EarlyView.
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho, Chun‐Wei Tung, B. Linju Yen, Chen‐Yi Weng, Ju‐Hsin Hsu, Ming‐Hsien Tsai, Salim Arrokhman, Pinpin Lin   +7 more
wiley   +1 more source

Mortality risk of ESBL producers in Escherichia coli bacteraemia: a comprehensive analysis using the PROBAC cohort. [PDF]

J Antimicrob Chemother
Olivares-Navarro P, Pérez-Rodríguez MT, Sousa A, Goikoetxea-Agirre AJ, Blanco Vidal MJ, Plata A, León E, Buzón-Martín L, Pulido-Navazo Á, Boix-Palop L, Retamar-Gentil P, Armiñanzas-Castillo C, Fernández-Natal I, Del Arco Jiménez A, Jover-Sáenz A, Fernández-Suárez J, Martín-Aspas A, Smithson-Amat A, Bahamonde-Carrasco A, Natera-Kindelán C, Martínez Pérez-Crespo PM, López-Hernández I, Rodríguez-Baño J, López-Cortés LE, PROBAC/GEIRAS-SEIMC/SAMICEI .   +24 more
europepmc   +1 more source

Unraveling the impact of dog‐friendly spaces on urban–wildland pumas and other wildlife

Wildlife Biology, EarlyView.
As the most widespread large carnivore on the planet, domestic dogs Canis lupus familiaris can pose a major threat to wildlife, even within protected areas (PAs). Growing human presence in PAs, coupled with increasing pet dog ownership underscores the urgency to understand the influence of dogs on wildlife activity and health.
Alys Granados, Zara McDonald, Katie McPherson, David Stoner   +3 more
wiley   +1 more source

Abnormal Splicing of <i>GALC</i> Transcripts Underlies Unusual Cases of Krabbe Disease. [PDF]

Biomedicines
Domínguez-Ruiz M, Chico JL, López-Marín L, Stanescu S, Crujeiras P, Rodrigues D, Heras-Alonso ML, Torremocha R, Meijón-Ortigueira MDM, Muñoz-Díez P, Lanza VF, Colón C, Villarrubia J, Belanger A, Castillo FJD.   +14 more
europepmc   +1 more source

Full‐length transcriptome profiling of true bug mitochondrial genomes reveals the unique transcriptional regulation during insect evolution

Insect Science, EarlyView.
The mitogenome was transcribed into complete primary polycistrons on both strands. The heteropteran mitochondrial transcription termination factor (HmTTF) functions as a bidirectional attenuator rather than a terminator, and co‐evolution of HmTTF and the binding sites was observed.
Shiwen Xu, Yuange Duan, Ling Ma, Qiaoqiao Liu, Fan Song, Wanzhi Cai, Hu Li   +6 more
wiley   +1 more source

Patient-Reported Incident Measure (PRIM) tools for reporting patient safety incidents: protocol for a scoping review. [PDF]

BMJ Open
Osorio D, Plana MN, Rubio-Valera M, Muñoz-Miguel J, Bolíbar I, Franco MT, Secanell-Espluga M, Soler-Font M, Fernández-Torres P, Suclupe S, Salas-Gama K, Torres-López D, Ferreira-González I, FIS-PRIMs Research Group.   +13 more
europepmc   +1 more source

Comparative Molecular Insights into Developmental and Behavioral Toxicity Induced by Octocrylene and Ethylhexyl Salicylate Exposure on Zebrafish

Integrative Zoology, EarlyView.
This study compared the ecological toxicity of organic ultraviolet filters, octocrylene (OC) and ethylhexyl salicylate (EHS), on zebrafish embryos and larvae. EHS exhibited higher acute toxicity, causing increased mortality, hypoactive behavior at 50 mg/L, and disruptions in lipid homeostasis, while OC primarily affected hypoxia response and ...
Xiaoyang Lu, Li Sun, Jiao Chen, Jing Wang, Miao Guan, Shixia Xu   +5 more
wiley   +1 more source

High temporal resolution monitoring of illicit drug consumption across England via wastewater analysis

Addiction, EarlyView.
Abstract Aim To monitor community‐level consumption of 20 illicit drugs across urban areas of England using wastewater‐based epidemiology (WBE) surveillance at high temporal resolution. Design, setting, cases This study was conducted over a 12‐month period in 2022 sampling 24‐hour composite wastewater samples at 15 wastewater treatment plants (WWTPs ...
Helena Rapp‐Wright, Keng Tiong Ng, Derryn Grant, William Francis, Margarita White, Dimitris Evangelopoulos, Yuxing Liu, Konstantina Dimakopoulou, Sofia Zafeiratou, Dylan Wood, Chryshanthi Christy, Stav Friedman, Timothy W. Gant, Klea Katsouyanni, Leon P. Barron   +14 more
wiley   +1 more source

Clinical validation of liquid biopsy-RECIST (LB-RECIST) in metastatic colorectal cancer (mCRC) patients: findings from the PLATFORM-B study. [PDF]

ESMO Open
Martelli V, Vidal J, Gibert J, Fernández-Rodríguez MC, Linares J, García-Alfonso P, Páez D, Alonso V, Gomez-España MA, Guix M, Santos C, Duran G, Élez E, Garcia-Carbonero R, Ferreiro R, Pineda E, Sastre J, Cano MT, Manzano JL, Losa F, Aranda E, Rivera F, Sibilio A, Toledo R, Tabernero J, Salazar R, Bellosillo B, Montagut C, Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD).   +28 more
europepmc   +1 more source