Results 41 to 50 of about 468,211 (255)
Papéis Avulsos de Zoologia, 2006 Calliini (Coleoptera, Cerambycidae, Lamiinae): descrições, homonímia, novo registro e chave para as espécies de Graminea Thomson, 1864. Espécies novas descritas: Paracallia giesberti sp. nov. da Bolívia (Cochabamba), Colombicallia albofasciata sp. nov. e
Ubirajara R. Martins +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
O arquivo pessoal de José Petronilo de Santa Cruz: o livreiro-editor da Livraria Duas Cidades
Revista do Instituto de Estudos Brasileiros, 2020 RESUMO Este artigo investiga o arquivo pessoal de José Petronilo de Santa Cruz e abarca aspectos (auto)biográficos e da cultura escrita relacionada à Livraria Duas Cidades, fundada e dirigida por Santa Cruz na cidade de São Paulo.
Hugo Quinta, Wilton Carlos Lima da Silva
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Publicación Electrónica de la Asociación Paleontológica Argentina, 2019 Litopterna from fossiliferous exposures of the Santa Cruz Formation (Early–Middle Miocene) along the Río Santa Cruz, Patagonia Argentina, are analyzed and described.
Gabriela Ines Schmidt +3 more
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Sectores e ideologías en los conflictos sociales del extremos sur argentino (1919-1921)
Universum, 2006 Los conflictos sindicales previos a las grandes huelgas de 1921-1922 en Santa Cruz, muestran el carácter sectorial y transnacional de los enfrentamientos sociales del extremo sur argentino.
Rosario Güenaga
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Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2002 Analisaram-se amostras de água do mar de cinco pontos da Baía de Guanabara quanto ao número mais provável (NMP) de coliformes totais e de Escherichia coli usando-se o método fluorogênico, e verificaram-se o pH, a salinidade e a temperatura dos locais de ...
A.A. Pinheiro Jr. +3 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source