Results 51 to 60 of about 1,430,831 (294)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Publicación Electrónica de la Asociación Paleontológica Argentina, 2019 Four specimens of primates were collected from the Santa Cruz Formation (Early–Middle Miocene) during expeditions undertaken by the Museo de la Plata, Museo Argentino de Ciencias Naturales “Bernardino Rivadavia”, and Duke University in 2013, 2014, and ...
Richard Frederick Kay +1 more
doaj
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Evaluación de la Avifauna Para Uso Ecoturístico en Humedales del Sur de Santa Cruz
Informes Científicos y Técnicos (Universidad Nacional de la Patagonia Austral), 2017 Este estudio comprende una valoración cuali-cuantitativa de las especies de aves asociadas ecológicamente a humedales del sur de la provincia de Santa Cruz, Argentina.
Ariel Almendras +2 more
doaj +1 more source
Granitoides peraluminosos con andalucita y cordierita magmáticas en la sierra de Velasco: implicancias para el orógeno famatiniano. [PDF]
, 2005 La combinación de estudios petrológicos, geoquímicos y de química mineral en el sector noreste de la sierra de Velasco, a la latitud de la localidad de Santa Vera Cruz, revelan la presencia de una unidad ígnea peraluminosa con andalucita (Si = 3,85, Al
Alasino, Pablo H. +4 more
core +1 more source
Measurement of Inclusive Production of Light Charged Hadrons at BaBar [PDF]
, 2013 Inclusive hadron production cross sections in e+e-collisions shed light on the fundamental fragmentation and hadronization processes. We present measurements of the inclusive spectra of charged pions, kaons and protons in hadronic events at a center-of ...
Muller, David
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
El registro biológico humano de la costa meridional de Santa Cruz
Revista Argentina de Antropología Biológica, 2010 RESUMEN La costa patagónica constituye un sector de riesgo para el registro arqueológico, asociado a factores naturales y antrópicos. Al mismo tiempo, la conservación de las colecciones bioarqueológicas, destacándose la pérdida de restos óseos e ...
Jorge A. Suby +2 more
doaj +2 more sources
Publicación Electrónica de la Asociación Paleontológica Argentina, 2019 The Thematic Volume “Early-Middle Miocene Paleontology in the Río Santa Cruz, Southern Patagonia, Argentina. 130 years since Ameghino, 1887” deals with the geology, chronology and the fossils of the Santa Cruz Formation in the Río Santa Cruz recovered in
Juan C. Fernicola +3 more
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