Results 61 to 70 of about 110,649 (250)

Exploiting structure-activity relationships of QS-21 in the design and synthesis of streamlined saponin vaccine adjuvants [PDF]

, 2020
We report the design, synthesis, immunological evaluation, and conformational analysis of new saponin variants as promising vaccine adjuvants. These studies have provided expedient synthetic access to streamlined adjuvant-active saponins and yielded ...
Corzana, Francisco [0000-0001-5597-8127], J. Jimenez-Barbero, J. Anguita, Poveda, A, Fernandez-Tejada, A, A. Poveda, N. Sacristan, Jimenez-Barbero, J, Diego Barriales, Anguita, Juan [0000-0003-2061-7182], Mattia Ghirardello, Ane Ruiz-de-Angulo, Ruiz-De-Angulo, Ane, Anguita, J, Sacristan, Nagore, A. Fernandez-Tejada, A. Ruiz-de-Angulo, Ghirardello, Mattia [0000-0002-2855-4801], Barriales, Diego, Corzana, F, M. Ghirardello, Fernández-Tejada, Alberto [0000-0002-1680-0059], Poveda, Ana, F. Corzana, Jiménez-Barbero, Jesús [0000-0001-5421-8513], D. Barriales, Nagore Sacristan   +26 more
core   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

Steroidal Glycosides of Cordyline australis [PDF]

, 2006
The n-butanol extract of aerial parts of Cordyline australis demonstrated antifungal activity. n-Butanol and chloroform extracts of dried or fresh leaves of C. australis afforded a steroidal glycoside, which was identified as 5α-spirost-25(27)-en-3β-ol 3-
Korkashvili, Tamar
core  

Compound Abrus cantoniensis Extract Alleviates AFB1‐Induced Liver Injury by Regulating PI3K‐AKT Pathway and Gut Microbiota/Butyrate Metabolism

Advanced Science, EarlyView.
ACCE has a good alleviating effect on AFB1‐induced liver injury, and this alleviating effect is related to the PI3K‐AKT pathway regulated by ACCE and the butyrate metabolism of gut microbiota. ABSTRACT Aflatoxin B1 (AFB1) is a potent hepatotoxin commonly ingested through contaminated food. Abrus cantoniensis Hance, a traditional Chinese medicinal herb,
Hongjie Hu, Ming cheng, Shiqi Zheng, Huixin Liu, Xiaofang Wei, Wenwen Yang, Hongchun Yang, Liuyang Yuan, Li Jiang, Jie Chen, Linglong Zhao, Yanchao Guo, Hongbin Si   +12 more
wiley   +1 more source

Calibration curves, LODs, LOQ, and precision for notoginseng saponin R₁, ginseng saponin Rg₁, ginseng saponin Re, ginseng saponin Rb₁ and ginseng saponin Rd.

, 2016
Calibration curves, LODs, LOQ, and precision for notoginseng saponin R1, ginseng saponin Rg1, ginseng saponin Re, ginseng saponin Rb1 and ginseng saponin Rd.
Xiao-he Xiao (124522), Ding-kun Zhang (3207618), Hai-zhu Zhang (3207609), Lu-qi Huang (3207624), Gui-lin Yan (3207627), Li-juan Cao (3207621), Gang Li (34549), Yan-hui Wang (3207615), Jia-bo Wang (124500), Da-hui Liu (3207612)   +9 more
core   +1 more source

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

Advanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu, Ruijuan Zhang, Yixin Duan, Shuqi Huo, Xiang Zhang, Yibin Xing, Lingjing Ma, Tiran Jiang, Xingyu Chen, Qingmin Sun   +9 more
wiley   +1 more source

The Diversity of Four Anti-nutritional Factors in Common Bean

Horticultural Plant Journal, 2016
Anti-nutritional factors such as lectins, saponin, trypsin inhibitor and phytic acid are endogenous substances in the common bean (Phaseolus vulgaris L.).
Rui Shang, Hua Wu, Rui Guo, Qin Liu, Lei Pan, Jianan Li, Zhihui Hu, Chanyou Chen   +7 more
doaj   +1 more source

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72hi Macrophages and Blocking CXCL12–CXCR4 Axis to Inhibit Endothelial Pyroptosis

Advanced Science, EarlyView.
CD72hi macrophages drive endothelial pyroptosis and accelerate atherosclerosis through CXCL12–CXCR4‐mediated immune–vascular crosstalk. Ilexoside K suppresses this pathogenic communication by modulating CXCR4‐dependent endothelial responses, reducing inflammation and plaque progression. These findings reveal a macrophage–endothelial regulatory axis and
Xingling He, Sijing Li, Jiahui Chen, Liyu Lin, Xinyu Li, Xiaojiao Zhang, Yihui Zhang, Xingling Chen, Jinjian Guo, Zhongqi Yang, Lu Lu, Shihao Ni   +11 more
wiley   +1 more source

WARU LEAF (Hibiscus tiliaceus) AS SAPONIN SOURCE ON In vitro RUMINAL FERMENTATION CHARACTERISTIC [PDF]

Journal of the Indonesian Tropical Animal Agriculture, 2011
The effect of waru leaf (Hibiscus tiliaceus) supplementation as saponin source on ruminal fermentation characteristics were studied using in vitro gas production techniques. Rumen fluid was taken from fistulated Ongole crossbreed cattle.
L. Istiqomah, H. Herdian, A. Febrisantosa, D. Putra   +3 more
doaj  

Fermentation Potentials of Baobab Pulp Extract in Soy Yoghurt Production

AgriFood: Journal of Agricultural Products for Food, EarlyView.
The research work was about the importance of sourcing for alternative inoculants to replace the main inoculants regularly used for yoghurt production. The search for baobab pulp extract as replacement yielded result, as soy yoghurt was successfully produced.
Adegbola Oladele Dauda, Nahim Mokolade Adeagbo, Quadri Idowu Akinremi, Taofiqat Damilola Maiyaki, Adedamola Israel Abioye, Zulfiqoh Tolani AbdulAkeem, Damilare Johnson Folaranmi   +6 more
wiley   +1 more source