Results 41 to 50 of about 110,649 (250)

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

open access: yesAdvanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song   +5 more
wiley   +1 more source

Endogenous resistance to insect pests in alfalfa: engineering for enhanced resistance [PDF]

open access: yes, 1997
Alfalfa (Medicago sativa) is a valuable forage crop grown throughout the World. While the crop is resistant to attack by many insect pests, it is subject to potentially severe losses through the action of several specific pests, which are adapted to ...
Mazahery-Laghab, Hojjatollah   +1 more
core  

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

open access: yesAdvanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt   +16 more
wiley   +1 more source

PENGARUH INTENSITAS CAHAYA TERHADAP BIOMASSA DAN KADAR SAPONIN KALUS GINSENG JAWA (Talinum paniculatum Gaertn.) PADA BERBAGAI WAKTU KULTUR [PDF]

open access: yes, 2014
The aims of this research was to study the effects of light intensity on callus biomass and saponin content of ginseng jawa (Talinum paniculatum Gaertn.). Callus induced from leaf explants on solid Murashige and Skoog (MS) medium supplemented by 2
Alwiyah, Afifatul   +2 more
core   +3 more sources

ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites

open access: yesAdvanced Science, EarlyView.
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng   +9 more
wiley   +1 more source

Feeding Response to Tea Saponin in Chicks Given Diet Selection

open access: yesThe Journal of Poultry Science, 2001
In order to evaluate the involvement of taste in the decreased feed intake due to tea saponin, the preference for a diet containing saponin or cholesterol was studied in chicks given diet selection.
Hiroshi Ueda, Gen Shigemizu
doaj   +1 more source

Effect of gibberellic acid combined with saponin on shoot elongation of Asparagus officinalis

open access: yes, 2010
Effect of gibberellic acid (GA3) combined with saponin on shoot elongation of Asparagus officinalis was evaluated in tissue culture. Addition of saponin to GA3 supplemented Murashige and Skoog (MS) basal medium showed a dose depended effect on shoot ...
V. Saharan
core   +1 more source

SAPONIN RICH FRACTION OF BAUHINIA VARIEGATA LINN. AMELIORATES KIDNEY STONE FORMATION IN RATS [PDF]

open access: yes, 2022
The present study was planned to know the effect of saponin-rich extract of Bauhinia variegata Linn. (SREBV) in ethylene glycol induced urolithiasis model.
Tejal Gandhi, Hital Shah, Anjali Patel
core   +2 more sources

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen   +7 more
wiley   +1 more source

Expansion Microscopy Reveals the Spatial Association of Therapeutic Antibody–Receptor Complexes With Cholesterol‐Rich Membrane Domains

open access: yesAngewandte Chemie, EarlyView.
We report a super‐resolution strategy that maps cholesterol‐rich membrane domains in whole, intact cells with an effective spatial resolution of ∼40 nm by combining expansion microscopy with a perfringolysin O domain 4 probe. This approach enables direct visualization of the spatial association between CD20 and CD38 complexes and cholesterol‐rich ...
Gang Wen   +9 more
wiley   +2 more sources

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