Results 41 to 50 of about 82,181 (261)

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

Advanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker, Elodie L. Rey, Clara Stanschewski, Regina Wendenburg, Annabella Klemmer, Markéta Macho, Venkatesh P. Thirumalaikumar, Noha O. Saber, Aleksandra Skirycz, Alisdair R. Fernie, Mark Tester, Saleh Alseekh   +11 more
wiley   +1 more source

Pemanfaatan Senyawa Metabolit Sekunder Tanaman (Tanin dan Saponin) dalam Mengurangi Emisi Metan Ternak Ruminansia

Jurnal Sain Peternakan Indonesia, 2016
Peternakan ruminansia merupakan sektor yang sangat penting dalam menyediakan sumber protein hewani. Namun seiring perkembangannya mendapat beberapa kendala terkait dengan produksi metan dari ternak ruminansia yang berdampak negatifbagi penurunan ...
N. Hidayah
doaj   +1 more source

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

Evaluation of the effectiveness of saponin biosurfactants in enhancing aqueous-plus-micellar phase solubility of naphthalene oily discharge component [PDF]

Acta Periodica Technologica
The micellar solubilization of naphthalene by the natural non-ionic surfactant saponin, obtained from Sapindus mukorossi, was assessed based on its micellar properties. The isolation and purification of saponin were conducted using the microwave-assisted
Ziri Fatima Zohra, Mimanne Goussem, Benghalem Abderrezak, Belbali Abdelhak   +3 more
doaj   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Saponin Extracts Utilization as Dietary Additive in Ruminant Nutrition: A Meta-Analysis of In Vivo Studies

Animals
The present meta-analysis aimed to determine the underlying effects of different saponins extracted from different sources on the production performance, milk yield, digestibility, rumen fermentation, blood metabolites, and nitrogen utilization of ...
Yulianri Rizki Yanza, Agung Irawan, Anuraga Jayanegara, Fitri Ramadhani, Adib Norma Respati, Ainissya Fitri, Cecep Hidayat, Vincent Niderkorn, Adam Cieslak, Malgorzata Szumacher-Strabel, Rahmat Hidayat, Ujang Hidayat Tanuwiria   +11 more
doaj   +1 more source

WARU LEAF (Hibiscus tiliaceus) AS SAPONIN SOURCE ON In vitro RUMINAL FERMENTATION CHARACTERISTIC [PDF]

Journal of the Indonesian Tropical Animal Agriculture, 2011
The effect of waru leaf (Hibiscus tiliaceus) supplementation as saponin source on ruminal fermentation characteristics were studied using in vitro gas production techniques. Rumen fluid was taken from fistulated Ongole crossbreed cattle.
L. Istiqomah, H. Herdian, A. Febrisantosa, D. Putra   +3 more
doaj  

ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites

Advanced Science, EarlyView.
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng, Peiyuan Chai, Xiayuhe Pei, Yiwen Chen, Xiaoshuai Huang, Bei Liu, Yiqian Wu, Junlin Teng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

The Diversity of Four Anti-nutritional Factors in Common Bean

Horticultural Plant Journal, 2016
Anti-nutritional factors such as lectins, saponin, trypsin inhibitor and phytic acid are endogenous substances in the common bean (Phaseolus vulgaris L.).
Rui Shang, Hua Wu, Rui Guo, Qin Liu, Lei Pan, Jianan Li, Zhihui Hu, Chanyou Chen   +7 more
doaj   +1 more source