Results 61 to 70 of about 995,592 (330)
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Emerging Infectious Diseases, 2004 To the Editor: An outbreak of severe acute respiratory syndrome (SARS) occurred from February to May 2003 in Hong Kong, China, Singapore, and Canada. According to the World Health Organization, 1,755 people were infected in Hong Kong; 386 of these were healthcare workers.
Tsang, H, Scudds, R, Chan, E
openaire +5 more sources
FEBS Open Bio, EarlyView.Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
A Wideband Wearable Antenna with AMC Ground Plane for WBAN Applications [PDF]
Radioengineering, 2022 A flexible wearable antenna with wideband characteristics and having a conical radiation pattern which is suitable for ON body application is presented. To realize a compact antenna size, characteristic modal (CM) analysis is performed initially, and the
S. Bhattacharjee +3 more
doaj
FEBS Open Bio, EarlyView.Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui +3 more
wiley +1 more source
Remote Sensing, 2019 Radar altimetry in the context of sea ice has mostly been exploited to retrieve basin-scale information about sea ice thickness. In this paper, we investigate the sensitivity of altimetric waveforms to small-scale changes (a few hundred meters to about ...
Wiebke Aldenhoff +2 more
doaj +1 more source
Screening of cytotoxic or cytostatic flavonoids with quantitative Fluorescent Ubiquitination-based Cell Cycle Indicator-based cell cycle assay [PDF]
Royal Society Open Science, 2018 The Fluorescent Ubiquitination-based Cell Cycle Indicator (FUCCI) system can be used not only to study gene expression at a specific cell cycle stage, but also to monitor cell cycle transitions in real time. In this study, we used a single clone of FUCCI-
Young-Hyun Go +8 more
doaj +1 more source
Spatial Autoregressive Model of Tuberculosis Cases in Central Java Province 2019
Cauchy: Jurnal Matematika Murni dan Aplikasi, 2022 Tuberculosis is an infectious disease caused by infection with the bacterium Mycobacterium tuberculosis. Central Java is one of the three provinces with the highest tuberculosis cases in Indonesia.
Hasrat Ifolala Zebua +1 more
doaj +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Synthesis and Activity of New Schiff Bases of Furocoumarin
Heterocyclic Communications, 2020 Furocoumarins, such as 8-MOP, are the most common medications used to relieve the symptoms of vitiligo clinically. Some furocoumarins also showed excellent performance in an anti-bacterial assay.
Xie Huijun +4 more
doaj +1 more source