Results 191 to 200 of about 21,278 (246)
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Isolation and characterization of cardiac sarcolemma
Biochimica Et Biophysica Acta - Biomembranes, 1979A procedure was developed for the isolation of cardiac sarcolemmal vesicles. These vesicles are enriched about ten-fold (with respect to the tissue homogenate) in K+-stimulated p-nitrophenylphosphatase, (Na+ + K+)-ATPase, 5'-nucleotidase activities and sialic acid content, all of which are believed to be components of the sarcolemma.
Donald Bers, D M Bers
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Calcium binding in cardiac sarcolemma [PDF]
Canadian Journal of Physiology and Pharmacology, 1979 The relationship between calcium binding and ATPase activity has been investigated for guinea pig cardiac sarcolemma. The concentrations of calcium ions and of ATP were the main factors in determining the amount of calcium bound. With a saturating concentration of ATP, at low calcium concentrations (0.1 mM) more than 50% of the total calcium bound was
N C, Morcos, A L, Jacobson
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Biophysical analysis of the mechanical properties of the sarcolemma [PDF]
Canadian Journal of Physiology and Pharmacology, 1970 This paper attempts to explain the complex mechanical properties of the sarcolemma of single muscle fibers. Previously published measurements on retraction zones of frog semitendinosus fibers were used as a basis for computation. A somewhat slack system of helical fibers in the sarcolemma can adequately account for the observations.
R W, Fields, J J, Faber
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Cardiomyocyte damage control in heart failure and the role of the sarcolemma [PDF]
Journal of Muscle Research and Cell Motility, 2019 The cardiomyocyte plasma membrane, termed the sarcolemma, is fundamental for regulating a myriad of cellular processes. For example, the structural integrity of the cardiomyocyte sarcolemma is essential for mediating cardiac contraction by forming ...
Ashraf Kitmitto +2 more
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Journal of Molecular and Cellular Cardiology, 1984
Experiments in mammalian ventricle in which calcium (Ca) is removed from and replaced to arterial perfusate indicate that a component of Ca important in contractile control is bound to rapidly exchangeable cellular sites. These sites appear to be in rapid equilibrium with extracellular Ca and are replenished, beat-to-beat, from the extracellular source.
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Experiments in mammalian ventricle in which calcium (Ca) is removed from and replaced to arterial perfusate indicate that a component of Ca important in contractile control is bound to rapidly exchangeable cellular sites. These sites appear to be in rapid equilibrium with extracellular Ca and are replenished, beat-to-beat, from the extracellular source.
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Changes in the sarcolemma of the hypothyroid heart
Biochemical and Biophysical Research Communications, 1978Abstract Sarcolemmal membranes prepared from the hearts of thyroidectomised sheep showed a fall of more than 90% in both 5′-nucleotidase activity and the number of β-adrenergic receptor sites. A fall of more than 60% in both Na + +K + ATPase and adenyl cyclase activities also occurred.
R M, Smith +2 more
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Phosphorylation of the Sarcoplasmic Reticulum and Sarcolemma
Annual Review of Physiology, 1982The ,a-adrenergic actions of catecholamines represent a key control mecha nism that regulates the metabolic, electrical, and mechanical performance of the myocardium. Cyclic AMP( cAMP) serves as the intracellular second messenger for these regulatory processes in that ,a-adrenergic activation of a sarcolemmal adenylate cyclase causes intracellular ...
M, Tada, A M, Katz
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Characterization of rat myocardial sarcolemma
Journal of Molecular and Cellular Cardiology, 1981Sarcolemma (SL) was isolated from the hearts of rats by the procedure of Philipson et al. and was found to be of high purity by the use of electron microscopy and marker enzyme analysis. In the SL fraction the sarcolemmal marker enzyme Na+, K+-ATPase was enriched about 33-fold (without SDS stimulation) compared to the crude homogenate.
G F, Tibbits +5 more
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Biochemistry of the Sarcolemma
1985In animal cells plasma membrane constitutes the cell boundary and acts as the permeability barrier for controlling the transport of water and solutes into and out of the cell. The plasma membrane also receives information and plays important roles in cell-cell interaction and in cell growth and development.
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Cardiac Sarcolemma: Compositional Adaptation to Exercise
Science, 1981Marked changes were observed in the lipid composition of highly purified plasma membranes isolated from the hearts of rats subjected to daily treadmill running. Compared to sedentary controls, sarcolemmal content of total phospholipid and phosphatidylserine in the trained group was increased 23 and 50 percent, respectively.
G F, Tibbits +3 more
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