Results 41 to 50 of about 18,467 (180)
BCL11B is up-regulated by EWS/FLI and contributes to the transformed phenotype in Ewing sarcoma.
PLoS ONE, 2013 The EWS/FLI translocation product is the causative oncogene in Ewing sarcoma and acts as an aberrant transcription factor. EWS/FLI dysregulates gene expression during tumorigenesis by abnormally activating or repressing genes.
Elizabeth T Wiles +3 more
doaj +1 more source
Interventional oncology in children: Where are we now?
Journal of Medical Imaging and Radiation Oncology, EarlyView.Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel +1 more
wiley +1 more source
Recent advances in targeted therapy for Ewing sarcoma [version 1; referees: 2 approved]
F1000Research, 2016 Ewing sarcoma is an aggressive, poorly differentiated neoplasm of solid bone that disproportionally afflicts the young. Despite intensive multi-modal therapy and valiant efforts, 70% of patients with relapsed and metastatic Ewing sarcoma will succumb to ...
Kathleen I. Pishas, Stephen L. Lessnick
doaj +1 more source
Personalized Cancer Vaccines in the Clinical Trial Pipeline
Asia-Pacific Journal of Clinical Oncology, EarlyView.This study analyzes the current landscape of personalized cancer vaccine clinical trials, highlighting trends in vaccine platforms, trial phases, and geographic distribution. Peptide and dendritic cell vaccines dominate early‐stage research, with promising immune responses observed in melanoma, glioblastoma, and urothelial cancer trials.
Liudmila Iamukova, Elena Alferova
wiley +1 more source
EWS/FLI1 target genes and therapeutic opportunities in Ewing sarcoma
Frontiers in Oncology, 2015 Ewing sarcoma family of tumors are aggressive bone malignancies that affect children and young adults. Ewing sarcoma is the second most common primary bone malignancy in pediatric patients.
Florencia eCidre, Javier eAlonso
doaj +1 more source
European Journal of Dental Education, EarlyView.ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer +4 more
wiley +1 more source
Characteristics of human Ewing/PNET sarcoma models
Annals of Saudi Medicine, 2011 Ewing/PNET (peripheral neuroepithelioma) tumors are rare aggressive bone sarcomas occurring in young people. Rare-disease clinical trials can require global collaborations and many years. In vivo models that as accurately as possible reflect the clinical
Teicher Beverly +5 more
doaj
Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The FEBS Journal, EarlyView.The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
Fine needle aspiration cytology diagnosis of paravertebral extraosseus Ewing′s sarcoma
Journal of Cytology, 2010 Extraskeletal Ewing′s sarcoma (EES) is a rare tumor. Paravertebral Ewing′s sarcoma requires more extensive therapy as compared to Ewing′s sarcoma of bone.
Buch Archana +4 more
doaj
Primary Ewing′s sarcoma of occipital bone
Indian Journal of Radiology and Imaging, 2006 Ewing′s sarcoma commonly involves the long bones. Primary Ewing′s sarcoma of the cranium is rare and is difficult to distinguish from other tumors involving the cranium. Radiological features and immuno-histochemistry are helpful in diagnosing this tumor.
RK Kaza, MS Sandhu, V Ojili
doaj +1 more source