Results 81 to 90 of about 208,351 (246)

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source

Bronchopulmonary Kaposi's sarcoma

Respiratory Medicine Case Reports, 2015
Kaposi's sarcoma (KS) is a highly vascular tumour, which was first described by the Hungarian dermatologist Moritz Kaposi Kohn before the discovery of the human immunodeficiency virus (HIV). Historically, KS has been linked to immunosuppression or to elderly male patients, especially in relation to diffuse cutaneous KS.
Bashar, Nada, Innes, Nicholas, Orrell, Julian   +2 more
openaire   +3 more sources

Remembering the forgotten child: the role of immune checkpoint inhibition in patients with human immunod eficiency virus and cancer. [PDF]

, 2019
Patients with human immunodeficiency virus (HIV) infection have a high risk of developing virally-mediated cancers. These tumors have several features that could make them vulnerable to immune checkpoint inhibitors (ICIs) including, but not limited to ...
Adashek, Jacob J, Galanina, Natalie, Junior, Pedro Nazareth Aguiar, Kurzrock, Razelle   +3 more
core  

Risk of Cancer among Commercially Insured HIV-Infected Adults on Antiretroviral Therapy. [PDF]

, 2016
The objective of this study was to explore the cancer incidence rates among HIV-infected persons with commercial insurance who were on antiretroviral therapy and compare them with those rates in the general population. Paid health insurance claims for 63,
Ambinder, Richard F, Casper, Corey, Dhakal, Ishwori, Haigentz, Missak, Krown, Susan E, Lee, Jeannette Y, Mitsuyasu, Ronald T, Noy, Ariela, Palefsky, Joel M   +8 more
core   +3 more sources

Human Mesenchymal Stem Cells of Diverse Origins Support Persistent Infection with Kaposi’s Sarcoma-Associated Herpesvirus and Manifest Distinct Angiogenic, Invasive, and Transforming Phenotypes

mBio, 2016
Kaposi’s sarcoma (KS), a highly angiogenic and invasive tumor often involving different organ sites, including the oral cavity, is caused by infection with Kaposi’s sarcoma-associated herpesvirus (KSHV).
Myung-Shin Lee, Hongfeng Yuan, Hyungtaek Jeon, Ying-hua Zhu, Seungmin Yoo, S. Shi, B. Krueger, R. Renne, Chun Lu, Jae U. Jung, Shou-Jiang Gao   +10 more
semanticscholar   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

Medicinal Research Reviews, EarlyView.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro, Sara Rossi, Stefania Butini, Sandra Gemma, Gabriele Carullo, Giuseppe Campiani   +5 more
wiley   +1 more source

Cyclosporine -induced Kaposi Sarcoma; a Case Report of an Adolescent Male with Steroid-resistant Nephrotic Syndrome [PDF]

, 2018
Although there are many reported cases of immunosuppressive-induced Kaposi sarcoma in renal transplant patients on immunosuppressive therapy, a similar report of Kaposi sarcoma among steroid-resistant nephrotic syndrome (SRNS) patients on ...
Adesina, Christiana Temilade, Anigilaje, Emmanuel Ademola, Raphael, Solomon   +2 more
core   +2 more sources

Sarcoma de Kaposi ocular. Presentación de un caso.

Gaceta Médica Espirituana, 2012
Fundamento: el sarcoma de Kaposi es una enfermedad tumoral descrita por primera vez por el médico húngaro Morita Kaposi en 1872 y puede presentarse con marcada frecuencia en pacientes seropositivos como enfermedad marcadora de sida. Presentación de caso:
Axel López Valdés, Vivian María Couce Herrera, Erians Valdés Pérez, Roxana María Almanza Alarcón, Edelby Escobar Carmona   +4 more
doaj  

Kaposi sarcoma-associated herpesvirus-associated malignancies: epidemiology, pathogenesis, and advances in treatment.

Seminars in Oncology, 2015
Kaposi sarcoma associated herpesvirus (KSHV), a γ2-herpesvirus, also known as human herpesvirus-8, is the etiologic agent of three virally associated tumors: Kaposi sarcoma, a plasmablastic form of multicentric Castleman disease (KSHV-MCD), and primary ...
M. Bhutani, M. Polizzotto, T. Uldrick, R. Yarchoan   +3 more
semanticscholar   +1 more source

Exploring the Hemoglobin T to R2 Path Using Gaussian Elastic Network Correlation Map Distance

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Proteins are dynamic and undergo conformational changes. These changes may affect the motions executed by different regions of the proteins and are reflected in the motion correlation map. A method to accurately measure these changes is presented and exemplified on a set of tetrameric Hemoglobin structures.
Yuval Valenci, Dror Tobi
wiley   +1 more source