Results 111 to 120 of about 734,103 (389)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Real-World Efficacy and Safety of Anti-PD-1 Antibody Plus Apatinib and Temozolomide for Advanced Acral Melanoma

Cancer Management and Research
Jiaran Zhang,1,* Huichun Tian,1,* Lili Mao,1 Caili Li,1 Xiaoting Wei,1 Junjie Gu,1 Xuan Wang,1 Li Zhou,2 Bin Lian,1 Bixia Tang,1 Xieqiao Yan,2 Siming Li,2 Chuanliang Cui,1 Zhihong Chi,1 Xinan Sheng,2 Jun Guo,1 Lu Si1 1Department of ...
Zhang J, Tian H, Mao L, Li C, Wei X, Gu J, Wang X, Zhou L, Lian B, Tang B, Yan X, Li S, Cui C, Chi Z, Sheng X, Guo J, Si L   +16 more
doaj  

An innovative staged prosthetic lengthening reconstruction strategy for osteosarcoma-related leg discrepancy

Scientific Reports
Correction of leg length discrepancy (LLD) in skeletally mature patients with osteosarcoma was rarely reported and quite challenging. This study aimed to propose a treatment strategy of staged lengthening and reconstruction with a standard static ...
Hairong Xu, Yuan Li, Feng Yu, Weifeng Liu, Lin Hao, Qing Zhang, Xiaohui Niu   +6 more
doaj   +1 more source

Clear Cell Sarcoma-Like Tumor of the Gastrointestinal Tract, Presenting as a Second Malignancy after Childhood Hepatoblastoma

Case Reports in Medicine, 2014
Clear cell sarcoma-like tumor of the gastrointestinal tract (CCSLGT) is a rare malignant neoplasm arising within the wall of the small bowel, stomach, or large bowel, predominantly in children and young adults.
Khin Thway, Ian Judson, Cyril Fisher
doaj   +1 more source

PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma. [PDF]

, 2016
BackgroundLeiomyosarcoma (LMS) is a common type of soft tissue sarcoma that responds poorly to standard chemotherapy. Thus the goal of this study was to identify novel selective therapies that may be effective in leiomyosarcoma by screening cell lines ...
Al-Awar, Rima, Babichev, Yael, Boutros, Paul C, Datti, Alessandro, Dickson, Brendan C, Gladdy, Rebecca A, Isaac, Methvin, Kabaroff, Leah, Prakesch, Michael, Sun, Ren X, Uehling, David, Venier, Rosemarie   +11 more
core   +2 more sources

Real-world data on the management of pazopanib-induced liver toxicity in routine care of renal cell cancer and soft tissue sarcoma patients [PDF]

, 2023
Kim Westerdijk, Stefanie D. Krens, Neeltje Steeghs, Winette T.A. van der Graaf, Eric T.T.L. Tjwa, Harm Westdorp, Ingrid M.E. Desar, Nielka P. van Erp   +7 more
openalex   +1 more source

Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations

Acta Neuropathologica, 2018
Patients with DICER1 predisposition syndrome have an increased risk to develop pleuropulmonary blastoma, cystic nephroma, embryonal rhabdomyosarcoma, and several other rare tumor entities.
C. Koelsche, M. Mynarek, D. Schrimpf, L. Bertero, J. Serrano, F. Sahm, D. Reuss, Yanghao Hou, D. Baumhoer, Christian Vokuhl, U. Flucke, I. Petersen, W. Brück, S. Rutkowski, S. C. Zambrano, J. G. Garcia Leon, R. D. Diaz Coronado, M. Gessler, Ò. M. Tirado, J. Mora, J. Alonso, X. García del Muro, M. Esteller, D. Sturm, J. Ecker, T. Milde, S. Pfister, A. Korshunov, M. Snuderl, G. Mechtersheimer, U. Schüller, David T. W. Jones, A. von Deimling   +32 more
semanticscholar   +1 more source

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Pedunculated pulmonary artery intimal sarcoma with poor uptake in 18F-FDG PET/CT: A case report [PDF]

, 2021
Takumi Takauchi, Ryosuke Murai, Kazunori Musiake, Yoko Akaike, Masaya Hirayama, Atsushi Ueda, Tatsuhiko Komiya, Kazushige Kadota   +7 more
openalex   +1 more source

Endothelial Cells Angiogenesis in Sulfated Glycosaminoglycan (GAG) Hydrogels Enhanced by Bioactive Glass‐Released Ions

Advanced Functional Materials, EarlyView.
A mechanically tunable hydrogel composed of gelatin, chondroitin sulfate and laminin promotes angiogenesis in vitro without the supplement of growth factors. Endothelial cells morphogenesis was further enhanced by medium conditioned with bioactive glass 58S‐released ions (Ca and Si), thus offering a promising strategy to vascularize 3D tissue ...
Marco Piazzoni, Ilaria Borghi, Francesca Cadamuro, Sophia Dalfino, Riccardo Campanile, Sofia Nizzolo, Valeria Cassina, Francesca Tallia, Julian R. Jones, Francesco Mantegazza, Sabrina Bertini, Lorenzo Moroni, Francesco Nicotra, Laura Russo   +13 more
wiley   +1 more source