Results 211 to 220 of about 698,336 (388)

Establishment of a patient‐derived drug‐resistant oral squamous cell carcinoma animal model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Patient‐derived xenograft (PDX) tissues from less‐responsive groups (larger tumors) were serially passaged. Sequential passaging and drug exposure in PDX models recapitulated clinical tumor evolution, enabling the development of drug‐resistant oral squamous cell carcinoma (OSCC) models. This study can offer methodological insights for precision therapy
Chuanni Feng   +8 more
wiley   +1 more source

Double gene mutations of LRSAM1 and REEP1 and a new REEP1 mutation site found in a patient with amyotrophic lateral sclerosis with subjective paresthesia: A case report

open access: yesIbrain, EarlyView., 2023
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by selective degeneration of upper and lower motor neurons. Leucine‐rich repeats and sterility α mutations in motif 1 (LRSAM1) has been proven to be involved in the pathogenesis of ALS.
Ji‐Yao Qin   +6 more
wiley   +1 more source

Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease.

open access: yesBlood, 1995
J. Soulier   +10 more
semanticscholar   +1 more source

Sarcoma [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1937
openaire   +2 more sources

Advances on Albumin‐Based Carriers for Anticancer Drug Delivery

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou   +4 more
wiley   +1 more source

Engineered Hydrogels Revolutionize Locoregional Cancer Immunotherapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review systematically summarizes the latest research progress on injectable hydrogels in cancer immunotherapy, highlighting their unique advantages in precise immune activation, local drug‐controlled release, and immune microenvironment remodeling. These features provide innovative solutions to overcome the bottlenecks of systemic side effects and
Jiyong Wei   +3 more
wiley   +1 more source

Progress in Biomimetic Microdevices for Anticancer Drug Screening and their Potential for Enhancing In Vivo Efficacy

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo   +2 more
wiley   +1 more source

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