Results 241 to 250 of about 556,852 (338)

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Histological and Immunohistochemical Characterization of a Histiocytic Sarcoma Associated With a Follicular Lymphoma in a Ring-tailed Lemur (Lemur catta). [PDF]

Vet Med Sci
Aradilla N, Canales R, Lorenzo-Bermejo T, Mainez M, Aguiló-Gisbert J, Marbella D, Pablo-Moreno JM, Rodríguez-Bertos A.   +7 more
europepmc   +1 more source

TGFβ IMPRINTED NK CELLS WITH CHEMOTHERAPY FOR RELAPSED SARCOMA: PART 1 RESULTS, A REPORT FROM THE NATIONAL PEDIATRIC CANCER FOUNDATION [PDF]

Bhuvana A. Setty, John E. Mullinax, Masanori Hayashi, Jun Yin, Erin Trovillion, Lars M. Wagner, Michael S. Isakoff, Matteo Trucco, Natalie Booth, Matthew S. Dietz, Alice A. Lee, Amy E. Armstrong, Matthew Campbell, Damon R. Reed, Lawrence S. Gazda, Margaret Lamb, Prithy C. Martis, Dean A. Lee   +17 more
openalex   +1 more source

Berberine alleviates cell pyroptosis in diabetic retinopathy by regulating AKT1, JUN, and STAT3

Ibrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li, Ji‐Lin Chen, Yi‐Jian Sun, Jia‐Fan Sun, Fatin Athirah Pauzi, Song‐Lin Zhu, Amy Yi Hsan Saik, Alan Han‐Kiat Ong   +7 more
wiley   +1 more source

Extraosseous Ewing's Sarcoma Mimicking a Retropharyngeal Abscess: A Rare Case

Eye &ENT Research, EarlyView.
Syed Zohaib Maroof Hussain, Priya Dhar, Madeleine Grand, Charles Hall, Declan Costello   +4 more
wiley   +1 more source

Pubertal timing and incident uterine cancer in the Sister Study cohort

International Journal of Cancer, EarlyView.
What's New? Younger age at menarche is an established risk factor for uterine cancer. Age at onset of breast development (thelarche), the earliest marker of pubertal estrogen exposure unopposed by progesterone, may also be relevant to uterine cancer risk, but this association has not been explored. Using data from the US prospective Sister Study cohort,
Ariayana N. Harrell, Katie M. O'Brien, Natalie D. Shaw, Dale P. Sandler, Mandy Goldberg   +4 more
wiley   +1 more source

From mechanism to phenotype: What fits in a basket trial

Epilepsia, EarlyView.
Kette D. Valente
wiley   +1 more source

No relevant pharmacokinetic interaction between the KRAS G12C inhibitor sotorasib and the direct oral anticoagulant rivaroxaban in healthy subjects

International Journal of Cancer, EarlyView.
What's New? Venous thromboembolism (VTE) is common in cancer patients, with direct oral anticoagulants, including rivaroxaban, recommended as first‐line therapy. However, oral anticoagulant use is limited due to the growing use of targeted therapy and concerns about drug‐drug interactions.
Esther M. Hollander, Alessandra I. G. Buma, Jenneke Leentjens, Paddy K. C. Janssen, Michel M. van den Heuvel, David M. Burger, Berber Piet, Rob ter Heine   +7 more
wiley   +1 more source

Age‐specific breast cancer incidence by subtype, TNM stage and screening status in Sweden 2008–2019 estimated with multiple imputation

International Journal of Cancer, EarlyView.
What's New? Breast cancer incidence in women increases with age, but which subtypes contribute the most at different ages remains unclear. Incidence patterns of breast cancer subtypes are typically under‐reported in population‐based studies due to a high proportion of cases lacking subtype information.
Leo Gkekos, Katrín Ásta Gunnarsdóttir, Keith Humphreys, Irma Fredriksson, Anna L. V. Johansson   +4 more
wiley   +1 more source

Cohort study of standardized treatment pathways by multidisciplinary tumor board decision making in patients with salivary gland malignancies

International Journal of Cancer, EarlyView.
What's New? The overall survival of patients with salivary gland malignancies has shown limited progress. Here, the authors evaluated the impact of establishing a multidisciplinary tumor board to ensure standardized diagnostic and treatment procedures at a certified cancer center.
Nils Feldmann, Gunnar Wichmann, Andreas Dietz, Markus Pirlich   +3 more
wiley   +1 more source