Results 241 to 250 of about 516,933 (343)

Tumor‐infiltrating B cells participate in shaping the immunosuppressive microenvironment in solid tumors

International Journal of Cancer, EarlyView.
Abstract Tumor‐infiltrating B cells (TIBs) exhibit dual roles in the tumor microenvironment (TME) of solid tumors. While they can enhance anti‐tumor immunity through antibody production and immune activation, certain subsets—such as regulatory B cells (Bregs) and immunosuppressive plasma cells—contribute to immune evasion by secreting inhibitory ...
Zhitong Li, Ziyang Shen, Yuxiang Sun, Pengcheng Zhu, Tongyan Liu, Rong Yin   +5 more
wiley   +1 more source

Incidence patterns and temporal trends of childhood cancer in Germany, 1980–2019: Forty years of childhood cancer registration in Germany

International Journal of Cancer, EarlyView.
What's New? Childhood cancer ranks among the leading causes of disease‐related deaths in children in high‐income countries. Established risk factors, however, account for only a small proportion of incident childhood cancers. In this report, the authors present the first long‐term assessment of temporal trends in childhood cancer incidence rates in ...
Friederike Erdmann, Maike Wellbrock, Claudia Trübenbach, Desiree Grabow, Martin Schrappe, Peter Kaatsch, Claudia Spix, Joachim Schüz, Cécile M. Ronckers   +8 more
wiley   +1 more source

An exceptional oncological enigma: primary renal Ewing sarcoma in a clinical context-a case report. [PDF]

Front Oncol
Tan WL, Rizuana IH, Lee BR, Fam XI.
europepmc   +1 more source

New cell lines expanding the diversity of Ewing sarcoma models

International Journal of Cancer, EarlyView.
What's New? A chromosomal translocation between the EWSR1 and ETS genes is the key oncogenic driver in Ewing sarcoma. EWSR1::FLI1, the most frequent fusion, is subdivided into different fusion types with unclear prognostic relevance. Here, the authors describe the establishment and characterization of four new, intrinsically immortal, patient‐derived ...
Maximilian Kerkhoff, Christiane Schaefer, Wilhelm G. Dirks, Dawid Krzeciesa, Maximilian Bretschneider, Pauline R. Plaumann, Wiebke K. Guder, Arne Streitbürger, Sonja Herter, Heike Peterziel, Ina Oehme, Felina Zahnow, Thomas G. P. Grünewald, Uta Dirksen   +13 more
wiley   +1 more source

Letter to the editor: "Budd-Chiari syndrome from pleomorphic sarcoma compressing the inferior vena cava: A case report". [PDF]

Radiol Case Rep
Aphale P, Dokania S, Shekhar H.
europepmc   +1 more source

Novel therapeutic strategy targeting STMN1 using chlorambucil‐conjugated pyrrole–imidazole polyamide in small cell lung cancer

International Journal of Cancer, EarlyView.
What's New? Small cell lung cancer (SCLC) is aggressive and difficult to treat but exhibits high levels of stathmin 1 (STMN1), a candidate therapeutic target. In this study, the authors synthesized a chlorambucil (Chb)‐conjugated pyrrole–imidazole polyamide (PIP) compound targeting the STMN1 promoter and DNA sequences and evaluated its efficacy in ...
Ryohei Yoshikawa, Takayoshi Watanabe, Yoichi Ohtaki, Toshikazu Bando, Hiroshi Sugiyama, Takuya Araki, Hideaki Yashima, Bilguun Erkhem‐Ochir, Haruka Okami, Gendensuren Dorjkhorloo, Ikuma Shioi, Toshiteru Nagashima, Natsuko Kawatani, Tomohiro Yazawa, Eiji Narusawa, Takayuki Kosaka, Osamu Kawashima, Mitsuhiro Kamiyoshihara, John D. Minna, Luc Girard, Ken Shirabe, Hiroki Nagase, Kimihiro Shimizu, Takehiko Yokobori   +23 more
wiley   +1 more source

High-grade endometrial stromal sarcoma presenting with multiple brain metastases: a case report. [PDF]

J Med Case Rep
Kono H, Toyoshima M, Ikki A, Shimada H, Suzuki S.   +4 more
europepmc   +1 more source

Kaposi sarcoma herpesvirus-associated cancers and related diseases

Current Opinion in HIV and AIDS, 2017
P. Goncalves, J. Ziegelbauer, T. Uldrick, R. Yarchoan   +3 more
semanticscholar   +1 more source

The epidemiology and pathogenesis of uterine fibroids

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Uterine fibroids, or leiomyomas, are the most common benign tumors of the female reproductive tract, ultimately affecting a majority of women worldwide, primarily during their reproductive years. While their origin appears genetic, manifesting in monoclonal tumors, diverse features and mechanisms contribute to their growth and further ...
Malcolm G. Munro, Svetlana N. Tchaikovski, Ally Murji   +2 more
wiley   +1 more source

Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas. [PDF]

Cancer Immunol Res
Berger HR, Maharana M, Mirabal J, Kurenbekova L, Delaidelli A, Dasgupta A, Gad AZ, Sheha MF, Kerr SS, Ozcan AI, Morris JS, Major AM, Hicks MJ, McKenna MK, Seon BK, Baker ML, Sorensen PH, Hegde M, Yustein JT, Ahmed N, Joseph SK.   +20 more
europepmc   +1 more source