Utilising omics approaches to understand Kaposi's sarcoma-associated herpesvirus [PDF]
Christopher B. Owen
openalex
Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa +2 more
wiley +1 more source
Treatment paradigms in undifferentiated pleomorphic sarcoma of bone: lessons learned from osteosarcoma and questions that remain commentary on: Bielack SS et al. J Cancer Res Clin Oncol (2026). [PDF]
Geçgel A, Peker P.
europepmc +1 more source
Upper Airway Obstruction due to Kaposi Sarcoma—Presenting Sign of HIV: Case Report and Review
This study presents a case of undiagnosed HIV presenting with Kaposi sarcoma (KS) of the head and neck with acute upper airway obstruction (UAO) and provides an updated scoping literature review to examine the patient characteristics, lesion characteristics, interventions, and outcomes of KS cases with UAO from the pharynx, larynx, and/or trachea.
Zachary A. Wykoff +3 more
wiley +1 more source
Protein glycosylation in lung cancer from a mass spectrometry perspective
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi +2 more
wiley +1 more source
Case Report: Complete remission of refractory Langerhans cell sarcoma following CLAG-M chemotherapy and allogeneic hematopoietic stem cell transplant. [PDF]
Mades A +8 more
europepmc +1 more source
Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley +1 more source
Case Report: A rare case of primary undifferentiated pleomorphic sarcoma of the renal pelvis with high PD-L1 expression and a misleading positive urine FISH. [PDF]
Li J, Wang X, Zhen J, Qi M.
europepmc +1 more source
Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source

