Results 171 to 180 of about 17,660 (277)

Structured neighboring-sarcomere switching is coupled to variable-reach internal length redistribution during hyperthermal sarcomeric oscillations in living cardiomyocytes. [PDF]

Biophys Physicobiol
Shintani SA.
europepmc   +1 more source

Caloric restriction and aerobic exercise differentially counteract muscle–tendon dysfunction following diet‐induced obesity in C57BL/6J mice

The Journal of Physiology, EarlyView.
Abstract figure legend Diet‐induced obesity induced fibro‐adipogenic remodelling of the muscle–tendon unit, characterized by increased fibrosis, reduced specific force, impaired relaxation kinetics, elevated hysteresis, and reduced aerobic capacity and glucose tolerance.
Leonardo Cesanelli, Petras Minderis, Andrej Fokin, Aivaras Ratkevicius, Ingrida Balnyte, Polzonetti Valeria, Tomas Venckunas, Cameron Hill, Danguole Satkunskiene, Hans Degens   +9 more
wiley   +1 more source

Zasp52 in Drosophila melanogaster indirect flight muscles can serve as a model system to investigate the function of clinical variants causing myopathies. [PDF]

G3 (Bethesda)
Medina-Quintana J, Akbari-Gakieh B, Lalonde MP, Liu T, Schöck F.   +4 more
europepmc   +1 more source

Modular Tissue-Engineered Motor Units Featuring Spinal Motor Neurons Innervating Self-Assembled Myofiber Bundles. [PDF]

Macromol Biosci
Hilman MC, Krizman EN, Mourkioti F, Das S, Cullen DK.   +4 more
europepmc   +1 more source

Actin and Myosin Filament Arrays Form at Different Times in Developing Sarcomeres in Xenopus Laevis

, 1998
Myofibril assembly requires the cell to join diverse components, correctly oriented, to the rest of the cell. It 1s not known if myosin and actin arrays that make up the sarcomere form separately (either spacially or temporally or both) or if they form ...
Taylor, Teresa Ann
core  

A Partitioned Coupling Approach for Electromechanics Simulations of Skeletal Muscles Using FEBio

Proceedings in Applied Mathematics and Mechanics, Volume 26, Issue 4, December 2026.
ABSTRACT This work presents a partitioned coupling approach for electromechanical simulations of skeletal muscles. For the first time, we couple our highly specialized electrophysiology solver, which computes both force generation in muscle cells and action potential propagation in muscle fibers, with an external finite element continuum mechanics ...
Carme Homs‐Pons, Yesid Villota‐Narváez, Lalith Kumar Doreti, Marian Klink, Robin Lautenschlager, Dominik Göddeke, Miriam Schulte, Oliver Röhrle   +7 more
wiley   +1 more source

The titin N2A-MARP signalosome constrains muscle longitudinal hypertrophy in response to stretch. [PDF]

Elife
van der Pijl R, Gohlke J, Strom J, Peters E, Shen S, Conijn S, Hourani Z, Lange S, Chen J, Langlais P, Labeit S, Granzier HL, Ottenheijm C.   +12 more
europepmc   +1 more source

Safe and Stable Germline Transmission of MSTN Mutations in Cattle

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT With the global population expected to reach 10 billion by 2050, sustainable livestock production is critical. Gene editing of the myostatin (MSTN) gene represents a promising strategy to enhance muscle growth in cattle. In this study, MSTN‐mutated founder (F0) cows were used to generate F1 offspring via ovum pick‐up, in vitro fertilization ...
Gyeong‐Min Gim, Bae Young Choi, Jeongbin Yi, Kyeong‐Hyeon Eom, Soo‐Young Yum, Dae‐Jin Jung, Do‐Yoon Kim, Bokyoung Yang, Jong‐Seo Kim, Donghwan Shim, Goo Jang   +10 more
wiley   +1 more source

Contractility Drives Cardiomyocyte Maturation and the Response to Nanopatterns. [PDF]

Circ Res
Sherer LA, Nagle A, Papadaki M, Edassery SL, McMillen TS, Yoo D, D'Amico L, Brambila-Diaz D, Maynard L, Qiao M, Davis J, Regnier M, Kirk JA.   +12 more
europepmc   +1 more source

MicroRNA–mRNA Networks in Skeletal Muscle of Tailored Pig Models for Dystrophinopathies

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are X‐linked dystrophinopathies caused by mutations in the dystrophin (DMD) gene. A common DMD‐causing mutation in humans is exon 52 deletion (DMDΔ52), which disrupts the reading frame and abolishes dystrophin expression.
Sarah Reschke, Alexander Graf, Frieder Hadlich, Florian Jaudas, Thomas Fröhlich, Michael Stirm, Nikolai Klymiuk, Stefan Krebs, Eckhard Wolf, Asghar Ali   +9 more
wiley   +1 more source