Results 161 to 170 of about 30,048 (267)

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Evolution of Cardiac Models Toward Recreating Biologically Relevant Multiaxial Mechanical Stimuli. [PDF]

Tissue Eng Part B Rev
Dey A, Klouda L, Saraf A.
europepmc   +1 more source

Restoration of neuromuscular function by mitochondrial transplantation in injured mouse skeletal muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Mice received chemical injury (cardiotoxin) in the tibialis anterior muscle of one limb, and the contralateral muscle was injected with phosphate‐buffered saline (PBS) as a sham control. Mice then received PBS or mitochondria suspended in PBS into the tail vein.
Stephen E. Alway, Peter J. Ferrandi, Hector G. Paez, Christopher R. Pitzer, Junaith S. Mohamed, Michael R. Deschenes, James A. Carson   +6 more
wiley   +1 more source

SarcGraph for High-Throughput Regional Analysis of Sarcomere Organization and Contractile Function in 2D Cardiac Muscle Bundles. [PDF]

MicroPubl Biol
Mohammadzadeh S, Tsan YC, Renberg A, Kobeissi H, Helms A, Lejeune E.   +5 more
europepmc   +1 more source

Caloric restriction and aerobic exercise differentially counteract muscle–tendon dysfunction following diet‐induced obesity in C57BL/6J mice

The Journal of Physiology, EarlyView.
Abstract figure legend Diet‐induced obesity induced fibro‐adipogenic remodelling of the muscle–tendon unit, characterized by increased fibrosis, reduced specific force, impaired relaxation kinetics, elevated hysteresis, and reduced aerobic capacity and glucose tolerance.
Leonardo Cesanelli, Petras Minderis, Andrej Fokin, Aivaras Ratkevicius, Ingrida Balnyte, Polzonetti Valeria, Tomas Venckunas, Cameron Hill, Danguole Satkunskiene, Hans Degens   +9 more
wiley   +1 more source

Location-Dependent Differences in Cardiac and Skeletal Muscle Dysfunction Associated With Truncating Titin (<i>ttn.2</i>) Variants. [PDF]

Circ Res
Santiago CF, Huttner IG, O'Brien AK, Amerudin MAB, Bennett PM, Cvetkovska J, Chand R, Holt M, Trivedi G, Wang LW, Yang X, Smith KA, Gautel M, Fatkin D, Hinits Y.   +14 more
europepmc   +1 more source

Presentation of preload and afterload to isolated heart preparations

The Journal of Physiology, EarlyView.
Abstract figure legend The heart can be isolated, and when this is so, it must be subjected to loading conditions. Over the past few decades, various loading methods have been developed to prescribe preload and afterload to isolated working‐heart preparations.
Esau Mhandu, Toan Pham, Kenneth Tran, Andrew J. Taberner, June‐Chiew Han   +4 more
wiley   +1 more source

Does eccentric strength training add sarcomeres in series and subtract sarcomeres in parallel?

Journal of Sport and Health Science
Bart Bolsterlee, Paolo Tecchio, Daniel Hahn, Brent J. Raiteri   +3 more
doaj   +1 more source

Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy

EMBO Journal, 2001
R. Nicol, N. Frey, G. Pearson, M. Cobb, James Richardson, E. Olson   +5 more
semanticscholar   +1 more source

The pseudokinase domain PK1 of UNC-89/obscurin is required for mitochondrial morphology and function in C. elegans. [PDF]

J Muscle Res Cell Motil
Matsunaga Y, Ghazal N, Heim A, Dorendorf T, Qadota H, Wang Y, Mayer TU, Mayans O, Kwong JQ, Benian GM.   +9 more
europepmc   +1 more source