Results 161 to 170 of about 17,660 (277)

Technical Criteria for Delimiting the Picanha Beef Cut: A Preliminary Study. [PDF]

J Food Sci
ABSTRACT The Picanha, obtained from the Biceps femoris muscle, is highly valued worldwide. No official standard precisely defines this cut, leading slaughterhouses to rely on subjective criteria such as weight, length, or the location of the “third vein”.
Barros IB, Rezende-de-Souza JH, Noguera DCLH, Blanco GBA, Rizoli C, Consonni SR, Pflanzer SB.   +6 more
europepmc   +2 more sources

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Zasp52's differentially expressed intrinsically disordered region confers thin filament stability at the Z-disc. [PDF]

Elife
Ho N, Schöck F.
europepmc   +1 more source

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

Myosin folding boosts solubility in cardiac muscle sarcomeres

JCI Insight
The polymerization of myosin molecules into thick filaments in muscle sarcomeres is essential for cardiac contractility, with the attenuation of interactions between the heads of myosin molecules within the filaments being proposed to result in ...
Colleen M. Kelly, Jody L. Martin, Michael J. Previs   +2 more
doaj   +1 more source

Polarized Light Microscopy for Quantitative Assessment of Sarcomere-Scale Structural Order in Cardiac Tissue. [PDF]

J Biophotonics
Piavchenko G, Venediktov A, Shamitko Z, Urazova K, Obelchakova M, Khabarova E, Ershov A, Kartashkina N, Grikh V, Smirnov V, Ramenskaya G, Yatskovskiy A, Meglinski I.   +12 more
europepmc   +1 more source

Advanced imaging and multi‐omics to characterize cardiomyocyte ageing and its electrocardiographic imprint in PKP2 arrhythmogenic cardiomyopathy

The Journal of Physiology, EarlyView.
Abstract figure legend We used a murine model of cardiomyocyte‐specific conditional knockout of plakophilin 2 (PKP2cKO, middle panel). Using advanced imaging technology, we unveiled distinct hallmarks of premature ageing in PKP2cKO cardiomyocytes, including DNA damage and loss of repressed heterochromatin at the nuclear periphery, and mitochondrial ...
Giorgia Bertoli, Kavya Phadke, Alessandro Cospito, Xianming Lin, Marina Cerrone, Joanna Abi Rizk, Michael Cammer, Yan Deng, Joseph Sall, Mingliang Zhang, Feng‐Xia Liang, Irene de Lázaro, Mario Delmar   +12 more
wiley   +1 more source

β-Adrenergic stimulation recruits additional contracting sarcomeres in cardiomyocytes. [PDF]

Cardiovasc Res
Li J, Sundnes J, Erdal MS, Hou Y, Norseng PA, Linke WA, Laasmaa M, Louch WE.   +7 more
europepmc   +1 more source

Sarcomere Gene Mutation correction [PDF]

European Heart Journal, 2018
Sanjiv, Kaul, Stephen B, Heitner, Shoukhrat, Mitalipov   +2 more
openaire   +2 more sources

Restoration of neuromuscular function by mitochondrial transplantation in injured mouse skeletal muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Mice received chemical injury (cardiotoxin) in the tibialis anterior muscle of one limb, and the contralateral muscle was injected with phosphate‐buffered saline (PBS) as a sham control. Mice then received PBS or mitochondria suspended in PBS into the tail vein.
Stephen E. Alway, Peter J. Ferrandi, Hector G. Paez, Christopher R. Pitzer, Junaith S. Mohamed, Michael R. Deschenes, James A. Carson   +6 more
wiley   +1 more source