Results 181 to 190 of about 19,099 (312)

PatternJ: an ImageJ toolset for the automated and quantitative analysis of regular spatial patterns found in sarcomeres, axons, somites, and more

Biology Open
Mélina Baheux Blin, Vincent Loreau, Frank Schnorrer, Pierre Mangeol   +3 more
doaj   +1 more source

Antisense-mediated regulation of exon usage in the elastic spring region of Titin modulates sarcomere function [PDF]

Selvi Celik, Ludvig Hyrefelt, Tomasz Czuba, Yuan Li, Juliana Assis Geraldo, Julia Martínez, Markus Johansson, Oscar André, Jane Synnergren, Joakim Sandstedt, Pontus Nordenfelt, Kristina Vukušić, J. Gustav Smith, Olof Gidlöf   +13 more
openalex   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

The Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite, Xin Zhou, Andreas Koschinski, Wan‐Hua Hong, Marilù Casini, Manuel Koch, Ursula Ravens, Remi Peyronnet, Manuela Zaccolo, Blanca Rodriguez   +9 more
wiley   +1 more source

Human Variant in the Cardiac Troponin I Switch Domain Causes Diastolic Dysfunction in a Novel Mouse Model

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Elizabeth Silver, Jason M. Duran, Betul Beyza Gunes, Axel J. Fenwick, Sofie Maisel, Tsui‐Min Wang, Ana Maria Manso, Marina Sampaio Cruz, Yusu Gu, Joshua Fong, Aysen Shathaya, Chao Chen, Angel Soto‐Hermida, Wei Feng, Yoshitake Cho, Julius Bogomolovas, Jill M. Gelow, Ahmad Masri, Kelly A. Frazer, Robert S. Ross, Ju Chen, Catherine A. Makarewich, Anthony Cammarato, Andrew D. McCulloch, Paul Bushway, Eric D. Adler   +25 more
doaj   +1 more source

Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities

The Journal of Physiology, EarlyView.
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley   +1 more source

Application of microscopic technique to assess the structure of beef by measurement of the length of sarcomeres

, 2012
Celem pracy była ocena stopnia zróżnicowania długości sarkomerów mięśnia podgrzebieniowego z mięsa wołowego bydła rasy Limousin przy zastosowaniu techniki mikroskopowej. Przygotowano preparat mikroskopowy z próby mięśnia podgrzebieniowego (Infraspinatus)
Barszczewski, J., Głąbski, K., Pogorzelski, G., Głąbska, D., Wierzbicka, A., Guzek, D.   +5 more
core  

An internal viscous element limits unloaded velocity of sarcomere shortening in rat myocardium.

, 1992
Pieter P. de Tombe, H E ter Keurs
openalex   +2 more sources

Computational model of haemodynamics during atrial fibrillation

The Journal of Physiology, EarlyView.
Abstract figure legend We developed a simplified computational model that replicates patient‐specific haemodynamics during both normal sinus rhythm and atrial fibrillation (AF). Our computational model comprises: (1) an electrical subsystem that generates unco‐ordinated atrial and irregular ventricular activation times characteristic of AF and (2) a ...
Felix Plappert, Pim J.A. Oomen, Clara E. Jones, Emmanouil Charitakis, Lars O. Karlsson, Pyotr G. Platonov, Mikael Wallman, Frida Sandberg   +7 more
wiley   +1 more source

Development of a Cardiac Sarcomere Functional Genomics Platform to Enable Scalable Interrogation of Human TNNT2 Variants

, 2020
Anthony M. Pettinato, Feria A. Ladha, David J. Mellert, Nicholas Legere, Rachel Cohn, Robert Romano, Ketan Thakar, Yusheng Chen, J. Travis Hinson   +8 more
openalex   +2 more sources

Sarcomere Gene Mutation correction [PDF]

European Heart Journal, 2018
Sanjiv, Kaul, Stephen B, Heitner, Shoukhrat, Mitalipov   +2 more
openaire   +2 more sources