Results 61 to 70 of about 67,770 (262)

In the search of molecular signature of sarcopenia in C. elegans [PDF]

arXiv, 2012
Age-related muscle decline, a condition referred to as sarcopenia and defined as loss in muscle mass and muscle strength over time, is one of the most pervasive problems of the elderly, such that significant declines in strength and mobility affects essentially every old person We have found that ageing C.
arxiv  

Combined effect of frailty and sarcopenia on postoperative complications in older adults undergoing curative surgery for hepato‐biliary‐pancreatic cancer

Annals of Gastroenterological Surgery, EarlyView.
A multivariable logistic regression model was performed using covariates that were significant in the bivariable analyses, including bile duct cancer, longer operative times, and greater blood loss. Prefrail or frail status combined with sarcopenia remained significant in this model (OR 4.74; 95% CI, 1.10–20.29; p = 0.04).
Norifumi Harimoto, Keishi Sugimachi, Tomohiro F. Nishijima, Tomino Takahiro, Tomonari Shimagaki, Yohei Mano, Emi Onishi, Masahiko Sugiyama, Yasue Kimura, Masaru Morita   +9 more
wiley   +1 more source

Sarcopenia and catastrophic health expenditure by socio‐economic groups in China: an analysis of household‐based panel data

Journal of Cachexia, Sarcopenia and Muscle, 2022
Background Sarcopenia was thought to be associated with adverse outcomes and will cause lots of health expenditure. But the relationship between sarcopenia and catastrophic health expenditure (CHE) had been little explored.
Chen Ye, Xu Zheng, Sumiya Aihemaitijiang, Ruoyu Wang, Mairepaiti Halimulati, Xiaojie Huang, Zhaofeng Zhang   +6 more
doaj   +1 more source

Osteopenic occult vertebral fracture is associated with poor oncological outcome in patients with hepatocellular carcinoma after hepatic resection

Annals of Gastroenterological Surgery, EarlyView.
Osteopenic occult vertebral fracture (OVF) was associated with poor long‐term outcomes in patients with HCC after hepatic resection. Osteopenic OVF had a poorer prognosis than that of patients with either osteopenia or OVF. Abstract Background Although osteopenia has been associated with poor outcomes in patients with hepatocellular carcinoma (HCC ...
Koichiro Haruki, Kenei Furukawa, Munetoshi Akaoka, Masashi Tsunematsu, Michinori Matsumoto, Tomohiko Taniai, Yoshihiro Shirai, Shinji Onda, Ryoga Hamura, Toru Ikegami   +9 more
wiley   +1 more source

A Prospective Cohort Study Evaluating Impact of Sarcopenia on Hospitalization in Patients on Continuous Ambulatory Peritoneal Dialysis

Scientific Reports
Data regarding the association of sarcopenia with hospitalization has led to inconclusive results in patients undergoing dialysis. The main goal of this research was to investigate the association between sarcopenia and hospitalization in Chinese ...
Lailiang Wang, Beixia Zhu, Congping Xue, Haixue Lin, Fangfang Zhou, Qun Luo   +5 more
doaj   +1 more source

Prognostic Impact of Bone Mineral Density Reduction During Neoadjuvant Chemotherapy (NAC) in Patients Undergoing NAC Followed by Esophagectomy for Esophageal Cancer

Annals of Gastroenterological Surgery, EarlyView.
The association between BMD reduction during NAC and the worse prognosis remains unknown, although NAC followed by esophagectomy is a standard treatment for advanced ESCC. This study appeared that BMD massive reduction was an independent prognostic factor on OS (HR, 3.30; 95% confidence interval [CI], 1.69–6.55) and RFS (HR, 2.08; 95% CI, 1.19–3.63 ...
Kazuhide Sato, Keita Takahashi, Yoshitaka Ishikawa, Naoko Fukushima, Takahiro Masuda, Takanori Kurogochi, Masami Yuda, Akira Matsumoto, Kazuto Tsuboi, Yuichiro Tanishima, Fumiaki Yano, Ken Eto   +11 more
wiley   +1 more source

Association of phase angle with sarcopenia in chronic musculoskeletal pain patients: a retrospective study

Journal of Orthopaedic Surgery and Research, 2023
Background In chronic musculoskeletal pain patients, detection of sarcopenia is of significant clinical interest. Phase angle, which can be measured through bioelectrical impedance analysis (BIA), can detect sarcopenia; however, the evidence in chronic ...
Hironori Tsuji, Tomoko Tetsunaga, Haruo Misawa, Keiichiro Nishida, Toshifumi Ozaki   +4 more
doaj   +1 more source

Multi‐Risk‐Level Sarcopenia‐Prone Screening via Machine Learning Classification of Sit‐to‐Stand Motion Metrics from Wearable Sensors

Advanced Intelligent Systems, EarlyView.
A machine learning approach utilizes micro inertial measurement units (μIMUs) for noninvasive sarcopenia screening through a sit‐to‐stand test. With 53 older participants wearing IMUs, 510 features are extracted across four motion phases. Five algorithms (support vector machine, K‐nearest neighbors, decision tree, linear discriminant analysis, and ...
Keer Wang, Hongyu Zhang, Clio Yuen Man Cheng, Meng Chen, King Wai Chiu Lai, Calvin Kalun Or, Yong Hu, Arul Lenus Roy Vellaisamy, Cindy Lo Kuen Lam, Ning Xi, Vivian Weiqun Lou, Wen Jung Li   +11 more
wiley   +1 more source

Vestibular and cochlear dysfunction in aging: Two sides of the same coin?

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 8, Issue 4, Page 308-314, December 2022., 2022
Abstract Objective Nonspecific complaints of hearing loss, vertigo, imbalance, and instability, without a defined etiology, are very prevalent in the elderly population, with a great impact on morbidity and mortality in this age group. The objectives of this study were to verify whether there is age‐related vestibular dysfunction and to test the ...
Cátia Azevedo, Sérgio Vilarinho, Ana Sousa Menezes, Fernando Milhazes Mar, Luís Dias   +4 more
wiley   +1 more source

Corrin Ring Modification in Peptide Drug Development – a Brief History of “Corrination”

ChemMedChem, EarlyView.
This review highlights the applications of vitamin B12 conjugation (“corrination”) to peptides in the field of peptide‐based therapeutics, focusing on improved physio‐chemical properties, targeted/localized drug delivery, and enhanced oral bioavailability.
Nancy Cham, Robert P. Doyle
wiley   +1 more source