PPAR agonists for the treatment of cholestatic liver diseases: Over a decade of clinical progress. [PDF]
Hayes CM +4 more
europepmc +1 more source
Liver Organoids From Hepatocytes of Healthy Humans and Non-alcoholic Fatty Liver Disease (NAFLD) Patients Display Multilineage Architecture and can be Used to Develop an <i>In Vitro</i> Model of Steatohepatitis. [PDF]
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Current Drug Development Pipeline for MASLD and MASH: Focusing on Cardiovascular Comorbidities. [PDF]
Prikhodko VA, Okovityi SV.
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Efficacy and safety of PPAR agonists in primary biliary cholangitis: a systematic review and meta-analysis. [PDF]
Liao W, Fu S, Yang A, Yang Y.
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The Personalized Management of Primary Biliary Cholangitis in the Era of Precision Medicine: Current Challenges and Future Perspectives. [PDF]
Romeo M +10 more
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Selective PPARα Modulator (SPPARMα) in the Era of the MASLD Pandemic: Current Insights and Future Prospects. [PDF]
Sugihara T.
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Alleviation of pulmonary fibrosis by the dual PPAR agonist saroglitazar and breast milk mesenchymal stem cells via modulating TGFß/SMAD pathway. [PDF]
Attia SH +3 more
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Saroglitazar is commonly used in India for managing hypertriglyceridemia in diabetes. This meta-analysis evaluated the efficacy and safety of saroglitazar in hypertriglyceridemia.Electronic databases were searched for RCTs involving diabetes patients receiving saroglitazar in intervention arm, and placebo/lipid/diabetes medication in the control arm ...
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