Results 71 to 80 of about 1,274,904 (321)

SARS‐CoV‐2 infection with bilateral intralabyrinthine hemorrhage

Clinical Case Reports, 2022
A 47‐year‐old woman presented with the complaint of sudden hearing loss associated with vertigo. Serological testing was positive for IgM and negative for IgG COVID‐19 antibodies, with no other associated factors.
Vagner Antonio Rodrigues daSilva, André Pinto Villarim, Monine Couto Farias Bem, Mauro Caldas Mendes Filho, Arthur Menino Castilho, Thiago Freire Pinto Bezerra, Joel Lavinsky   +6 more
doaj   +1 more source

In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Clinical Infectious Diseases, 2020
Background The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) first broke out in Wuhan (China) and subsequently spread worldwide. Chloroquine has been sporadically used in treating SARS-CoV-2 infection.
Xueting Yao, F. Ye, Miao Zhang, Cheng Cui, Baoying Huang, P. Niu, X. Liu, Li Zhao, Erdan Dong, Chunli Song, S. Zhan, R. Lu, Haiyan Li, W. Tan, Dongyang Liu   +14 more
semanticscholar   +1 more source

SARS CoV- 2 vaccination induces antibodies against cardiolipin

BMC Research Notes, 2022
Objective Cases of thrombosis have been reported after administration of SARS-CoV-2 vaccines, with controversial results relating to Oxford-AstraZeneca’s ChAdOx1-S.
George Krashias, Anna Pafiti, Elie Deeba, Christina Christodoulou, Marios Pantzaris, Anastasia Lambrianides   +5 more
doaj   +1 more source

Evidence for Gastrointestinal Infection of SARS-CoV-2

Gastroenterology, 2020
The new coronavirus (SARS-CoV-2) outbreak originating from Wuhan, China, poses a threat to global health. While it's evident that the virus invades respiratory tract and transmits from human to human through airway, other viral tropisms and transmission ...
Fei Xiao, Meiwen Tang, Xiaobin Zheng, Ye Liu, Xiaofeng Li, H. Shan   +5 more
semanticscholar   +1 more source

SARS‐CoV‐2 Omicron variant: Characteristics and prevention

MedComm, 2021
Coronavirus disease 2019 (COVID‐19) has brought about a great threat to global public health. Recently, a new severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) variant B.1.1.529 has been reported in South Africa and induced a rapid increase in
Xuemei He, Weiqi Hong, Xiangyu Pan, Guangwen Lu, Xiawei Wei   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Genomic Sequencing and Phylogenomics of Cowpox Virus

Viruses, 2022
Cowpox virus (CPXV; genus Orthopoxvirus; family Poxviridae) is the causative agent of cowpox, a self-limiting zoonotic infection. CPXV is endemic in Eurasia, and human CPXV infections are associated with exposure to infected animals. In the Fennoscandian
Diana Diaz-Cánova, Carla Mavian, Annika Brinkmann, Andreas Nitsche, Ugo Moens, Malachy Ifeanyi Okeke   +5 more
doaj   +1 more source

Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019

medRxiv, 2020
Summary Background The novel coronavirus SARS-CoV-2 is a newly emerging virus. The antibody response in infected patient remains largely unknown, and the clinical values of antibody testing have not been fully demonstrated.
Juanjuan Zhao, Q. Yuan, Haiyan Wang, Wei Liu, X. Liao, Yingying Su, Xin Wang, Jing Yuan, Tingdong Li, Jin-xiu Li, Shen Qian, Congming Hong, Fuxiang Wang, Yingxia Liu, Zhaoqin Wang, Qing He, Zhiyong Li, B. He, Tianying Zhang, Yang Fu, S. Ge, Lei Liu, Jun Zhang, N. Xia, Zheng Zhang   +24 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Early Multi-organ Point-of-Care Ultrasound Evaluation of Respiratory Distress During SARS-CoV-2 Outbreak: Case Report [PDF]

, 2020
Introduction: Coronavirus disease 2019 (COVID-19) is caused by the virus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).  Several case series from Italy and China have highlighted the lung ultrasound findings of this disease ...
Becherer-Bailey, Graham, Farrow II, Robert, Mantuani, Daniel, Nagdev, Arun   +3 more
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