Results 71 to 80 of about 1,242,031 (332)

Reliable and accurate diagnostics from highly multiplexed sequencing assays [PDF]

, 2020
Scalable, inexpensive, and secure testing for SARS-CoV-2 infection is crucial for control of the novel coronavirus pandemic. Recently developed highly multiplexed sequencing assays (HMSAs) that rely on high-throughput sequencing can, in principle, meet ...
Bloom, Joshua S., Booeshaghi, A. Sina, Cooper, Aaron R., Gehring, Jase, Kosuri, Sriram, Lubock, Nathan B., Luebbert, Laura, Pachter, Lior, Simpkins, Scott W.   +8 more
core  

Evolutionary Multi-Objective Design of SARS-CoV-2 Protease Inhibitor Candidates

, 2020
Computational drug design based on artificial intelligence is an emerging research area. At the time of writing this paper, the world suffers from an outbreak of the coronavirus SARS-CoV-2.
A Alhossary, CA Lipinski, CA Nicolaou, D Douguet, D Weininger, E van der Horst, E Zitzler, GR Bickerton, H Nguyen, HG Beyer, K Deb, L Zhang, N Brown, N Brown, O Trott, P Ertl, P Ertl, RF de Freitas, RV Devi, SCH Pegg, SS Kaplan, T Gaillard, T Krause, TT Wager, W Dai   +24 more
core   +1 more source

Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

Nature Communications, 2020
Since 2002, beta coronaviruses (CoV) have caused three zoonotic outbreaks, SARS-CoV in 2002–2003, MERS-CoV in 2012, and the newly emerged SARS-CoV-2 in late 2019. However, little is currently known about the biology of SARS-CoV-2.
Xiuyuan Ou, Yan Liu, X. Lei, Pei Li, Dan Mi, L. Ren, Li Guo, Ruixuan Guo, Ting Chen, Jiaxin Hu, Zichun Xiang, Z. Mu, Xing Chen, Jieyong Chen, Keping Hu, Q. Jin, Jianwei Wang, Zhaohui Qian   +17 more
semanticscholar   +1 more source

SARS-CoV-2 surveillance in a hospital and control of an outbreak on a geriatric ward using whole genome sequencing

Infection Prevention in Practice
Summary: Background: During the SARS-CoV-2 pandemic, dominant viral variants were repeatedly replaced by new variants with altered properties, frequently changing the dynamics of the infection event, as well as the effectiveness of vaccines and ...
Hanno Schmidt, Niels Lemmermann, Matthias Linke, Sven-Ernö Bikár, Stefan Runkel, Susann Schweiger-Seemann, Susanne Gerber, André Michel, Thomas Hankeln, Marina Veith, Wolfgang Kohnen, Bodo Plachter   +11 more
doaj   +1 more source

Evidence for Gastrointestinal Infection of SARS-CoV-2

Gastroenterology, 2020
The new coronavirus (SARS-CoV-2) outbreak originating from Wuhan, China, poses a threat to global health. While it's evident that the virus invades respiratory tract and transmits from human to human through airway, other viral tropisms and transmission ...
Fei Xiao, Meiwen Tang, Xiaobin Zheng, Ye Liu, Xiaofeng Li, H. Shan   +5 more
semanticscholar   +1 more source

Electronic Health Record-Based Surveillance for Community Transmitted COVID-19 in the Emergency Department [PDF]

, 2020
Introduction: SARS-CoV-2, a novel coronavirus, manifests as a respiratory syndrome (COVID-19) and is the cause of an ongoing pandemic. The response to COVID-19 in the United States has been hampered by an overall lack of diagnostic testing capacity.
Barclay-Buchanan, Ciara, Batt, Robert, Glazer, Joshua M., Hekman, Daniel J., Kuehnel, Nicholas, Patterson, Brian W., Pulia, Michael S., Ross, Joshua, Sharp, Brian   +8 more
core  

Monitoring of SARS‐CoV‐2 infection in mustelids

EFSA Journal, 2021
American mink and ferret are highly susceptible to severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), but no information is available for other mustelid species.
European Food Safety Authority and European Centre for Disease Prevention and Control, Anette Boklund, Christian Gortázar, Paolo Pasquali, Helen Roberts, Søren Saxmose Nielsen, Karl Stahl, Arjan Stegeman, Francesca Baldinelli, Alessandro Broglia, Yves Van Der Stede, Cornelia Adlhoch, Erik Alm, Angeliki Melidou, Grazina Mirinaviciute   +14 more
doaj   +1 more source

Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019

medRxiv, 2020
Summary Background The novel coronavirus SARS-CoV-2 is a newly emerging virus. The antibody response in infected patient remains largely unknown, and the clinical values of antibody testing have not been fully demonstrated.
Juanjuan Zhao, Q. Yuan, Haiyan Wang, Wei Liu, X. Liao, Yingying Su, Xin Wang, Jing Yuan, Tingdong Li, Jin-xiu Li, Shen Qian, Congming Hong, Fuxiang Wang, Yingxia Liu, Zhaoqin Wang, Qing He, Zhiyong Li, B. He, Tianying Zhang, Yang Fu, S. Ge, Lei Liu, Jun Zhang, N. Xia, Zheng Zhang   +24 more
semanticscholar   +1 more source

Aptamer‐based strategies against SARS‐CoV‐2 viruses

BMEMat, 2023
The COVID‐19 pandemic, caused by SARS‐CoV‐2, has seriously threatened human life and security in recent years and has had a serious impact on economic development. A range of strategies, including antibodies, small‐molecule agents and vaccines, have been
Yihao Huang, Ximing Chen, Jialu Zhang, Wenhai Tian, Siwen Liu, Rachel Chun‐Yee Tam, Chaoyong Yang, Yanling Song   +7 more
doaj   +1 more source

Genomic Sequencing and Phylogenomics of Cowpox Virus

Viruses, 2022
Cowpox virus (CPXV; genus Orthopoxvirus; family Poxviridae) is the causative agent of cowpox, a self-limiting zoonotic infection. CPXV is endemic in Eurasia, and human CPXV infections are associated with exposure to infected animals. In the Fennoscandian
Diana Diaz-Cánova, Carla Mavian, Annika Brinkmann, Andreas Nitsche, Ugo Moens, Malachy Ifeanyi Okeke   +5 more
doaj   +1 more source