Results 151 to 160 of about 98,010,213 (261)

Cryo‐EM Analysis of Adenovirus Vector Reveals Purification Conditions Leading to Loss of Viral Fiber Proteins and Reduced Infectivity

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Vaccines and gene therapies require efficient delivery of genetic material to host cells. Viral vectors leverage viruses' ability to enter host cells to achieve this. Following the SARS‐CoV‐2 vaccine and novel gene therapies that utilize adenovirus vectors, there has been an increase in the demand for large‐scale production of vectors.
Betsy Widdicombe, Joseph D. Barritt, Nichakorn Pipatpadungsin, Braulio Carrillo Sanchez, Dale Stibbs, Lisa Cooper, Sarah L. Rouse, Daniel G. Bracewell   +7 more
wiley   +1 more source

Developing antibody tests for SARS-CoV-2 [PDF]

The Lancet, 2020
openaire   +2 more sources

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Prefrontal Planning Latency Associated With Age and Serological Evidence of Microbial Exposure

Chronic Diseases and Translational Medicine, EarlyView.
Planning latency versus age by group. Scatterplot showing individual observations (n = 53) stratified by fibromyalgia status. LOESS smoothing curves with 95% confidence intervals (shaded regions) illustrate the relationship within each group. Overall, rₛ = 0.394 (p = 0.003).
Basant K. Puri, Rosemarie Preyer, Gary S. Lee, Lucy Monaghan, Armin Schwarzbach   +4 more
wiley   +1 more source

Research Progress on V2CTx MXene‐Based Composites: Synthetic Strategies, Structure Design, and Multifunctional Applications

Carbon Energy, EarlyView.
This review systematically and comprehensively summarizes the latest research progress on V2CTx MXene. Focusing on the structural design strategies, particularly the construction of the V2CTx‐based hetero‐composite structure. Furthermore, widespread applications including electrochemical energy storage and conversion, as well as photocatalytic ...
Wenjun Zhu, Minghai Zhao, Min Fan, Jianmin Luo, Jian Tian, Xinhui Xia, Wenkui Zhang, Xinyong Tao, Yanxian Jin, Yang Xia   +9 more
wiley   +1 more source

SARS CoV-2 in tumor tissue in glioblastoma patients – preliminary study

Current Issues in Pharmacy and Medical Sciences
SARS-CoV-2 infection often causes neurological disorders. Experimental studies on an animal model have shown that SARS-CoV-2 is able to cross the blood-brain barrier. Researchers have also discovered that SARS-CoV-2 can infect glial cells.
Brzozowski Michal, Kolesnik Marcin, Michalski Aleksander, Drop Katarzyna, Polz-Dacewicz Malgorzata   +4 more
doaj   +1 more source

Serologic Testing for Middle East Respiratory Syndrome Coronavirus and SARS-CoV-2 Cross-Reactive Immune Responses, the Netherlands

Emerging Infectious Diseases
Cross-reactive SARS-CoV-2–specific antibodies could compromise the specificity of MERS-CoV serology, potentially leading to misclassification of infection history.
Merel R. te Marvelde, Anna Z. Mykytyn, Matthijs P. Raadsen, Alexandre H.J. Bouffier, Sivana Baptista Varela, Rory D. de Vries, Corine H. GeurtsvanKessel, Bart L. Haagmans   +7 more
doaj   +1 more source

Shared and Distinguishing Features of Late‐Onset Rheumatic Diseases Fulfilling Polymyalgia Rheumatica Classification Criteria

Arthritis &Rheumatology, EarlyView.
Kerem Abacar, Ala Altaie, Andrew Barr, Sarah L. Mackie, Kulveer Mankia, Dennis McGonagle   +5 more
wiley   +1 more source

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source