Results 121 to 130 of about 680,934 (308)

Follow-up SARS-CoV-2 serological study of a health care worker cohort following COVID-19 booster vaccination

open access: yesBMC Infectious Diseases
Background Studies have shown that Omicron breakthrough infections can occur at higher SARS-CoV-2 antibody levels compared to previous variants. Estimating the magnitude of immunological protection induced from COVID-19 vaccination and previous infection
Alexander Hönning   +11 more
doaj   +1 more source

Nucleotide analogues as inhibitors of SARS‐CoV Polymerase

open access: yesPharmacology Research & Perspectives, 2020
SARS‐CoV‐2, a member of the coronavirus family, has caused a global public health emergency. Based on our analysis of hepatitis C virus and coronavirus replication, and the molecular structures and activities of viral inhibitors, we previously reasoned ...
Jingyue Ju   +9 more
doaj   +1 more source

Molecular Crowding Modulates SARS‐CoV‐2 Aptamer Affinity

open access: yesSmall Structures, 2023
SARS‐CoV‐2 aptamer is a favorable candidate for the recognition and detection of SARS‐CoV‐2, owing to its small size and easy synthesis. However, the issue of compromised binding affinities in real samples and targeting mutant SARS‐CoV‐2 hinder wide ...
Ting Song   +6 more
doaj   +1 more source

Broad and durable antibody response after vaccination with inactivated SARS-CoV-2 in individuals with a history of 2003 SARS-CoV infection

open access: yesEmerging Microbes and Infections, 2022
In vaccinees who were infected with SARS-CoV in 2003, we observed greater antibody responses against spike and nucleoprotein of both SARS-CoV-2 and SARS-CoV after a single dosage of inactivated SARS-CoV-2 vaccine.
Huang Liang   +18 more
doaj   +1 more source

SARS‐CoV: Lessons learned; opportunities missed for SARS‐CoV‐2

open access: yesReviews in Medical Virology, 2020
SummarySARS‐CoV‐2 and Covid‐19 have made a retrospective analysis of other coronavirus diseases important, so this article reviews the history of the SARS‐CoV viral disease from 2003. Standard and clinical chemistry diagnostics were developed in response to the outbreak. The response to SARS is examined to determine if there were lessons learned before
openaire   +4 more sources

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Reporte N°26: Vigilancia activa de variantes de SARS-CoV-2. Análisis genómico de casos de variante Delta en la provincia de Córdoba y en la CABA. Actualización al 10/08/2021 [PDF]

open access: yes, 2021
Participantes en este reporte: Nodo de secuenciación y análisis de variantes del HNRG (CABA): Sofía Alexay; Dolores Acuña; Mercedes Nabaes; Guillermo Thomas; Laura Valinotto; Stephanie Goya; Mónica Natale; Silvina Lusso; Mariana Viegas; Alicia S ...
Gobierno de la Provincia de Córdoba. Ministerio de Salud. Laboratorio Central   +2 more
core  

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Hyperimmunized Chickens Produce Neutralizing Antibodies against SARS-CoV-2 [PDF]

open access: yes, 2022
The novel severe acute respiratory syndrome (SARS) coronavirus, SARS-CoV-2, is responsible for the global COVID-19 pandemic. Effective interventions are urgently needed to mitigate the effects of COVID-19 and likely require multiple strategies.
Rodrigo A. Gallardo   +12 more
core   +1 more source

Human neutralising antibodies elicited by SARS‐CoV‐2 non‐D614G variants offer cross‐protection against the SARS‐CoV‐2 D614G variant

open access: yesClinical & Translational Immunology, 2021
Objectives The emergence of a SARS‐CoV‐2 variant with a point mutation in the spike (S) protein, D614G, has taken precedence over the original Wuhan isolate by May 2020.
Cheryl Yi‐Pin Lee   +24 more
doaj   +1 more source

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