Results 111 to 120 of about 679,279 (310)

Systematic Comparison of Two Animal-to-Human Transmitted Human Coronaviruses: SARS-CoV-2 and SARS-CoV

, 2020
After the outbreak of the severe acute respiratory syndrome (SARS) in the world in 2003, human coronaviruses (HCoVs) have been reported as pathogens that cause severe symptoms in respiratory tract infections.
Yunlong Wang, Guo, Xiangqian, Xu, Jiabao, Wan Zhu, Jiabao Xu, Shizhe Zhao, Xiangqian Guo, Wang, Yunlong, Zhao, Shizhe, Abdalla, E. Abualgasim, Abualgasim Elgaili Abdalla, Xie, Longxiang, Longxiang Xie, Zhu, Wan, Tieshan Teng, Teng, Tieshan   +15 more
core   +1 more source

SARS-CoV-2 infects BCO.

, 2022
Immunolabeling of SARS-CoV-2 infected vehicle-treated organoid sections stained for TUNEL (white), SARS-CoV-2 N protein (green), and MAP2 (red) by confocal microscopy. Scale bar, 20 μm. The BCOs were fixed and analyzed 7 days post-infection. (MOV)
Simoni H. Avansini (3909700), Gabriela Goldberg (14053913), Jason W. Adams (14053907), Fabio Papes (3409028), Pinar Mesci (14053895), Cedric Snethlage (14053904), Aurian Saleh (14053901), Patrick T. Bruck (5726117), Yuan Pu (3509042), Ryan A. Szeto (14053910), Alysson R. Muotri (9030983), Roberto H. Herai (8892830), Sumit K. Chanda (11768006), Laura Martin-Sancho (6475421), Angela Macia (14053898), Angels Almenar-Queralt (187926), Xin Yin (149454), Janaina S. de Souza (11111100)   +17 more
core   +1 more source

Ultrasensitive Detection of Porcine Epidemic Diarrhea Virus Infections Using Multivalent DNA Nanostructure‐Enabled Lateral Flow Assay

Advanced Healthcare Materials, EarlyView.
A multivalent DNA nanostructure‐enabled lateral flow assay was developed for rapid, ultrasensitive detection of porcine epidemic diarrhea virus (PEDV) nucleocapsid protein. Designer net‐shaped DNA nanostructures (DNA‐Net) presenting PEDV‐specific aptamers achieved ~1000‐fold enhanced binding, enabling detection of viral copies with Ct ≤ 37.42 within 10
Saurabh Umrao, Akhila Naru, Dhanush Gandavadi, Mengxi Zheng, Saraswathi Lanka, Hyeongjun Cho, Chau Nguyen Minh Hoang, Jianqiang Zhang, Ying Fang, Xing Wang   +9 more
wiley   +1 more source

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source

Epidemiology, transmission dynamics and control of SARS: the 2002-2003 epidemic [PDF]

, 2004
This paper reviews current understanding of the epidemiology, transmission dynamics and control of the aetiological agent of severe acute respiratory syndrome (SARS).
Hedley, A, Leung, Gabriel M, Ghani, Azra C, Christophe Fraser, Lam, T, Anderson, RM, Ghani, AC, Lam, TH, Azra C. Ghani, Donnelly, C, Leung, GM, Fraser, C, Ferguson, Neil M, Fraser, Christophe, Donnelly, CA, Hedley, AJ, Christl A. Donnelly, Anderson, Roy M, Ferguson, NM, Riley, Steven, Roy M. Anderson, Leung, G, Hedley, Anthony J, Anthony J. Hedley, Ghani, A, Ferguson, N, Anderson, R, Donnelly, Christl A, Steven Riley, Riley, S, Neil M. Ferguson, Gabriel M. Leung, Tai H. Lam   +32 more
core   +1 more source

Evaluation of EPISEQ SARS-CoV-2 and a Fully Integrated Application to Identify SARS-CoV-2 Variants from Several Next-Generation Sequencing Approaches

, 2022
Whole-genome sequencing has become an essential tool for real-time genomic surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worldwide.
Ligeon, Véronique, Emmanuelle Santiago, Vignola, Alexandre, Véronique Ligeon, Josset, Laurence, Regue, Hadrien, Abel Betraoui, Magali Jaillard, Griffon, Aurélien, Brengel-Pesce, Karen, Destras, Gregory, Tournoud, Maud, Nathalie Mugnier, Bal, Antonin, Maud Tournoud, Alexandre Vignola, Laurence Josset, Aurélien Griffon, Bruno Simon, Santiago, Emmanuelle, Gregory Destras, Jaillard, Magali, Karen Brengel-Pesce, Simon, Bruno, Antonin Bal, Mugnier, Nathalie, Maxence Rambaud, Cheynet, Valérie, Hadrien Regue, Valérie Cheynet, Betraoui, Abel, Rambaud, Maxence   +31 more
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REGEN‐COV antibody combination in patients with lymphoproliferative malignancies and SARS‐CoV‐2 infection

eJHaem, 2022
Patients with lymphoproliferative diseases are at high risk for SARS‐CoV‐2‐related complications and mortality. The role of casirivimab and imdevimab (REGEN‐COV), a neutralizing antibody cocktail, to treat immunocompromised hemato‐oncological patients ...
Yotam Bronstein, Irit Avivi, Yael C Cohen, Eugene Feigin, Chava Perry, Yair Herishanu   +5 more
doaj   +1 more source

Electrically Readable Lateral Flow Assay Using Organic Transistors for Diagnostic Applications

Advanced Materials, EarlyView.
Electrolyte‐gated organic field‐effect transistors (EGOFETs) are integrated with lateral flow (LF) paper fluidics to create a reusable, portable, and low‐cost point‐of‐care (PoC) diagnostic test. The devices are validated for Human Immunoglobulin G detection, achieving high sensitivity (0.1 fm), selectivity, and reproducibility with rapid results in 20–
María Jesús Ortiz‐Aguayo, Carme Martínez‐Domingo, Diego Gutiérrez, Dean Kos, Marta Mas‐Torrent   +4 more
wiley   +1 more source

Viral Infection‐Inspired Autonomous Detection of Fusion‐Competent Viruses for Screening and Environmental Surveillance

Advanced Materials, EarlyView.
Inspired by viral entry mechanisms, the FUSION assay enables autonomous detection of respiratory viruses via membrane fusion–triggered CRISPR‐Cas13a activation. VEACON selectively fuses with fusion‐competent viruses, triggering fluorescence within confined vesicles.
Jae Chul Park, Yidam Song, Hyun‐Woo Choi, Jaeuk Sung, Harin Jin, WonSeok Gwak, Kirim Yoo, Soohwang Lee, Jongeon Park, Jeongmin Kim, Hye‐Jun Jo, Jahyun Koo, Youngdo Jeong, Kwan Hyi Lee, Seung‐Jung Kee, Hojun Kim   +15 more
wiley   +1 more source

IgG specific to SARS-CoV-2 RBD in (1) non-diagnosed for COVID-19 but positive for anti-SARS-CoV-2 IgG, (2) in patients hospitalized due to COVID-19, (3) and in vaccinated against SARS-CoV-2.

, 2022
IgG specific to SARS-CoV-2 RBD in (1) non-diagnosed for COVID-19 but positive for anti-SARS-CoV-2 IgG, (2) in patients hospitalized due to COVID-19, (3) and in vaccinated against SARS-CoV-2.
Amelia Kardaś (12041991), Krystyna Dąbrowska (315930), Kamil Barczyk (12042000), Aleksander Szymczak (7865159), Krzysztof Baniecki (12041979), Katarzyna Gembara (11603890), Zuzanna Kaźmierczak (7865156), Agnieszka Hoffmann (12041988), Artur Nahorecki (12041985), Wojciech Witkiewicz (674088), Aleksandra Pikies (12041982), Tomasz Klimek (12041997), Alina Szewczyk-Dąbrowska (12041994), Natalia Jędruchniewicz (7865168), Wiktoria Budziar (12041976), Marek Harhala (5873900)   +15 more
core   +1 more source