Results 91 to 100 of about 679,279 (310)
Monitoring of SARS‐CoV‐2 infection in mustelids
EFSA Journal, 2021 American mink and ferret are highly susceptible to severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), but no information is available for other mustelid species.
European Food Safety Authority and European Centre for Disease Prevention and Control +14 more
doaj +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
SARS-CoV-2 Punctuated Evolution
, 2022 The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) evolved slowly over the first year of the Coronavirus Disease 19 (COVID-19) pandemic with differential mutation rates across lineages. Here, we explore how this variation arose.
Chris Organ (8485672) +2 more
core +1 more source
Aptamer‐based strategies against SARS‐CoV‐2 viruses
BMEMat, 2023 The COVID‐19 pandemic, caused by SARS‐CoV‐2, has seriously threatened human life and security in recent years and has had a serious impact on economic development. A range of strategies, including antibodies, small‐molecule agents and vaccines, have been
Yihao Huang +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
BMC Infectious DiseasesBackground Studies have shown that Omicron breakthrough infections can occur at higher SARS-CoV-2 antibody levels compared to previous variants. Estimating the magnitude of immunological protection induced from COVID-19 vaccination and previous infection
Alexander Hönning +11 more
doaj +1 more source
Nucleotide analogues as inhibitors of SARS‐CoV Polymerase
Pharmacology Research & Perspectives, 2020 SARS‐CoV‐2, a member of the coronavirus family, has caused a global public health emergency. Based on our analysis of hepatitis C virus and coronavirus replication, and the molecular structures and activities of viral inhibitors, we previously reasoned ...
Jingyue Ju +9 more
doaj +1 more source
Molecular Crowding Modulates SARS‐CoV‐2 Aptamer Affinity
Small Structures, 2023 SARS‐CoV‐2 aptamer is a favorable candidate for the recognition and detection of SARS‐CoV‐2, owing to its small size and easy synthesis. However, the issue of compromised binding affinities in real samples and targeting mutant SARS‐CoV‐2 hinder wide ...
Ting Song +6 more
doaj +1 more source
Emerging Microbes and Infections, 2022 In vaccinees who were infected with SARS-CoV in 2003, we observed greater antibody responses against spike and nucleoprotein of both SARS-CoV-2 and SARS-CoV after a single dosage of inactivated SARS-CoV-2 vaccine.
Huang Liang +18 more
doaj +1 more source