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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified in 2020 and has led to an unprecedented global pandemic. Understanding the virology behind SARS-CoV-2 infection has provided key insights into our efforts to develop antiviral agents and control the COVID-19 pandemic.
Li, Yijia, Li, Jonathan Z.
openaire +3 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
T Cell responses to whole SARS Coronavirus in humans [PDF]
Effective vaccines should confer long-term protection against future outbreaks of severe acute respiratory syndrome (SARS) caused by a novel zoonotic coronavirus (SARS-CoV) with unknown animal reservoirs.
Douek, Daniel C. +54 more
core +1 more source
Expression of SARS-CoV-2 proteins from rVSVNJ-SARS-CoV-2. [PDF]
To check the expression of SARS-CoV-2 RBD, S1, and SF from rVSVNJ-SARS-CoV-2 infected cells, BHK-21 cells were infected with the virus at an MOI of 6. After six hours incubation at 37°C, cell lysates were prepared and protein expression was determined by
Taewoo Kim (1456888) +30 more
core +1 more source
SARS CoV- 2 vaccination induces antibodies against cardiolipin
Objective Cases of thrombosis have been reported after administration of SARS-CoV-2 vaccines, with controversial results relating to Oxford-AstraZeneca’s ChAdOx1-S.
George Krashias +5 more
doaj +1 more source
SummaryThe recent emergence of a new coronavirus (severe acute respiratory syndrome coronavirus‑2, SARS-CoV-2) that is transmitted efficiently among humans and can result in serious disease and/or death has become a global threat to public health and economy.
Heinz, Franz X., Stiasny, Karin
openaire +2 more sources
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
SARS-CoV-2 Aerosol and Intranasal Exposure Models in Ferrets [PDF]
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the worldwide COVID-19 pandemic. Animal models are extremely helpful for testing vaccines and therapeutics and for dissecting the viral and host factors that ...
John M. Dye +15 more
core +1 more source
SARS‐CoV‐2 Omicron variant: Characteristics and prevention
Coronavirus disease 2019 (COVID‐19) has brought about a great threat to global public health. Recently, a new severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) variant B.1.1.529 has been reported in South Africa and induced a rapid increase in
Xuemei He +4 more
doaj +1 more source
Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics [PDF]
Standl, Fabian +4 more
openaire +2 more sources

